Table 3

Comparison of single-nucleotide polymorphisms and Fibromyalgia Impact Questionnaire scores in patients from Mexico and Spain


Spaniards
Mexicans
Genotypes
25th percentile
Median
75th percentile
P value
25th percentile
Median
75th percentile
P value

rs6269








     AA
75.1
78.6
82.1

57.7
67.53
80.5

     AG
60.6
67.1
70.1
0.0001
68.7
77.5
80.67
0.193
     GG
51.1
56.3
56.7

41.01
66.77
79.17

rs4633








     CC
73.9
78.7
86.1

61.4
71.25
78.17

     CT
59.8
62.6
68.5
0.0001
60.7
71.29
82.7
0.785
     TT
51.1
56.2
56.7

57.7
66.21
85.47

rs4818








     CC
75.1
78.1
82.4

57.7
64.20
80.5

     GC
60.2
65.3
70.2
0.0001
68.74
77.5
81.58
0.054
     GG
51.7
56.2
61.7

60.43
66.33
73.17

rs4680








     AA
50.62
52.3
56.1

57.7
72.97
88.24

     AG
59.4
62.1
68.3
0.0001
62.7
74.35
83.60
0.284
     GG
72.8
78.6
85

59.9
68.74
76.46


Only single-nucleotide polymorphisms with significant associations in Spaniards are shown. In Mexicans, none was associated with the Fibromyalgia Impact Questionnaire.

Vargas-Alarcón et al. Arthritis Research & Therapy 2007 9:R110   doi:10.1186/ar2316