|
Comparison of single-nucleotide polymorphisms and Fibromyalgia Impact Questionnaire scores in patients from Mexico and Spain |
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| Spaniards |
Mexicans |
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| Genotypes |
25th percentile |
Median |
75th percentile |
P value |
25th percentile |
Median |
75th percentile |
P value |
|
|
||||||||
| rs6269 |
||||||||
| AA |
75.1 |
78.6 |
82.1 |
57.7 |
67.53 |
80.5 |
||
| AG |
60.6 |
67.1 |
70.1 |
0.0001 |
68.7 |
77.5 |
80.67 |
0.193 |
| GG |
51.1 |
56.3 |
56.7 |
41.01 |
66.77 |
79.17 |
||
| rs4633 |
||||||||
| CC |
73.9 |
78.7 |
86.1 |
61.4 |
71.25 |
78.17 |
||
| CT |
59.8 |
62.6 |
68.5 |
0.0001 |
60.7 |
71.29 |
82.7 |
0.785 |
| TT |
51.1 |
56.2 |
56.7 |
57.7 |
66.21 |
85.47 |
||
| rs4818 |
||||||||
| CC |
75.1 |
78.1 |
82.4 |
57.7 |
64.20 |
80.5 |
||
| GC |
60.2 |
65.3 |
70.2 |
0.0001 |
68.74 |
77.5 |
81.58 |
0.054 |
| GG |
51.7 |
56.2 |
61.7 |
60.43 |
66.33 |
73.17 |
||
| rs4680 |
||||||||
| AA |
50.62 |
52.3 |
56.1 |
57.7 |
72.97 |
88.24 |
||
| AG |
59.4 |
62.1 |
68.3 |
0.0001 |
62.7 |
74.35 |
83.60 |
0.284 |
| GG |
72.8 |
78.6 |
85 |
59.9 |
68.74 |
76.46 |
||
|
Only single-nucleotide polymorphisms with significant associations in Spaniards are shown. In Mexicans, none was associated with the Fibromyalgia Impact Questionnaire. | ||||||||
Vargas-Alarcón et al. Arthritis Research & Therapy 2007 9:R110 doi:10.1186/ar2316 |
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