Table 2 |
||||||
|
Genotype distribution of the six catechol-O-methyltransferase single-nucleotide polymorphisms in patients and healthy controls from Mexico and Spain |
||||||
| Spanish |
Mexican |
|||||
| Genotype |
Patients |
Controls |
P value |
Patients |
Controls |
P value |
| n (%) |
n (%) |
n (%) |
n (%) |
|||
|
|
||||||
| rs6269 |
||||||
| AA |
21 (27) |
14 (18) |
0.015a |
30 (53) |
17 (52) |
NS |
| AG |
42 (54) |
34 (42) |
21 (37) |
13 (39) |
||
| GG |
15 (19) |
32 (40) |
6 (10) |
3 (9) |
||
| rs4633 |
||||||
| CC |
28 (36) |
19 (24) |
NSa |
21 (37) |
17 (52) |
NS |
| CT |
36 (46) |
37 (46) |
28 (49) |
13 (39) |
||
| TT |
14 (18) |
24 (30) |
8 (14) |
3 (9) |
||
| rs4818 |
||||||
| CC |
19 (24) |
13 (16) |
0.001 |
30 (53) |
15 (46) |
NS |
| CG |
47 (60) |
33 (41) |
21 (36) |
12 (36) |
||
| GG |
12 (16) |
34 (43) |
6 (11) |
6 (18) |
||
| rs4680 |
||||||
| AA |
9 (12) |
22 (27) |
0.023a |
2 (4) |
4 (12) |
NS |
| AG |
40 (51) |
39 (49) |
32 (56) |
14 (42) |
||
| GG |
29 (37) |
19 (24) |
23 (40) |
15 (46) |
||
| rs20907 |
||||||
| AA |
31 (40) |
23 (29) |
NSa |
26 (46) |
15 (45.5) |
NS |
| AG |
34 (43) |
40 (50) |
24 (42) |
15 (45.5) |
||
| GG |
13 (17) |
17 (21) |
7 (12) |
3 (9) |
||
| rs16559 |
||||||
| AA |
36 (46) |
33 (41) |
NSa |
12 (21) |
10 (30) |
NSa |
| AG |
30 (39) |
35 (44) |
32 (56) |
15 (46) |
||
| GG |
12 (15) |
12 (15) |
13 (23) |
8 (24) |
||
|
|
||||||
|
aχ2 test; NS, not significant. |
||||||
|
Vargas-Alarcón et al. Arthritis Research & Therapy 2007 9:R110 doi:10.1186/ar2316 |
||||||
