|
Imbalance of baseline measures of standardized cartilage biomarkers and prediction of subsequent cartilage loss on magnetic resonance imaging |
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| Unadjusted OR (95% CI) |
R2 |
AUC |
P value |
Adjusted ORa (95% CI) |
|
|
|
|||||
| CTX/CPII |
0.72 (0.03, 16.66) |
0.001 |
0.52 |
0.84 |
0.53 (0.02, 13.23) |
| C2C/CPII |
<0.001 (<0.001, 1.14) |
0.04 |
0.60 |
0.05 |
0.001 (<0.001, 1.46) |
| C1,2C/CPII |
0.24 (0.002, 39.12) |
0.003 |
0.52 |
0.59 |
0.31 (0.002, 52.18) |
| C1,2C/C2C |
0.19 (0.02, 2.12) |
0.02 |
0.57 |
0.18 |
0.22 (0.02, 2.48) |
| Col2CTX/Cr ratio/C2C |
1.60 (0.31, 8.19) |
0.003 |
0.52 |
0.57 |
1.37 (0.26, 7.40) |
|
aAdjusted for age, gender, and body mass index. AUC, area under the curve; C2C, collagenase cleavage of triple-helical type II collagen; CI, confidence interval; Col2CTx, Crosslinked peptides from the C-telopeptide domain of type II collagen; CPII, C-propeptide of type II collagen; OR, odds ratio. | |||||
Hunter et al. Arthritis Research & Therapy 2007 9:R108 doi:10.1186/ar2314 |
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