Table 1

Clinicopathological characteristics of synovial tissues obtained by surgical biopsy and ultrasound-guided biopsy

Biopsy

Age (years)

Sex

Disease duration (years)

RF/aCCP

Disease-modifying antirheumatic drugs

Joint

Valid samples/total samples

Valid sections

Cumulative area (mm2)


S-SY1

65

Female

18

+/+

MTX

Wrist

3/3

9

24.47

S-SY2

44

Female

12

-/-

PDN

I MTP

3/3

9

37.72

S-SY3

63

Female

14

+/+

MTX + HCQ

II and III MTPs

3/3

9

44.02

S-SY4

46

Female

34

-/+

HCQ

Wrist

4/4

12

41.68

S-SY5

46

Female

17

-/-

LFN + PDN

Wrist

5/5

15

60.32

S-SY6

75

Female

7

-/-

MTX + PDN

MCPs

3/3

9

34.75

S-SY7

78

Female

8

-/-

MTX + PDN

MCPs

3/3

9

38.68

S-SY8

46

Male

2

-/+

MTX + PDN

MCPs

3/3

9

22.42

S-SY9

68

Female

5

-/-

MTX + HCQ + PDN

I MTP

3/3

9

45.01

U-SY1

23

Female

5

+/+

CYA + PDN

II MCP

4/8

12

16.86

U-SY2

59

Female

4

-/-

MTX + PDN

V MCP

5/8

15

17.64

U-SY3

64

Female

18

+/+

PDN

II PIP

10/12

30

38.28

U-SY4

61

Female

11

-/+

MTX + PDN

V MCP

3/12

9

7.29

U-SY5

69

Male

10

+/+

MTX + HCQ + PDN

II MCP

8/12

24

20.16

U-SY6

75

Male

11

+/+

HCQ + SLZ + PDN

V MCP

10/12

29

28.71

U-SY7

67

Female

7

-/+

MTX + HCQ + PDN

II MCP

8/12

23

8.82

U-SY8

62

Female

8

-/-

MTX + PDN

II MCP

7/12

20

8.43

U-SY9

61

Female

11

+/+

MTX + HCQ + PDN

II MCP

9/12

26

20.91


The good quality/overall number of collected sample rate and the number of valid sections obtained considering three different cutting levels are provided. The cumulative area is computed on overall sections for each patient. S-SY, surgical biopsy synovial tissue; U-SY, ultrasound-guided biopsy synovial tissue; RF/aCCP, rheumatoid factor/anticyclic citrullinated peptide antibodies; MTX, methotrexate: PDN, prednisone; HCQ, hydroxychloroquine; LFN, leflunomide; CYA, cyclosporine A; SLZ, sulfasalazine; MCP, metacarpophalangeal; MTP, metatarsophalangeal; PIP, proximal interphalangeal.

Scirè et al. Arthritis Research & Therapy 2007 9:R101   doi:10.1186/ar2302

Open Data