Microarray gene expression profiling of osteoarthritic bone suggests altered bone remodelling, WNT and transforming growth factor-β/bone morphogenic protein signalling
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* Corresponding author: Nicola L Fazzalari nick.fazzalari@imvs.sa.gov.au
Arthritis Research & Therapy 2007, 9:R100 doi:10.1186/ar2301
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Juan C Bustos-Valenzuela, Andre Fujita, Erik Halcsik, Jose M Granjeiro, Mari C Sogayar BMC Research Notes 2011, 4:370 (26 September 2011) Thirteen new genes involved in osteoblast differentiation induced by bone morphogenetic proteins (BMPs) have been identified, which could improve our understanding on the molecular mechanisms underlying bone repair.
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James M Wilkins, Lorraine Southam, Zehra Mustafa, Kay Chapman, John Loughlin BMC Medical Genetics 2009, 10:141 (19 December 2009) Two polymorphisms of the BMP5 gene demonstrate a significant association with female hip osteoarthritis, while functional analysis suggests one of these polymorphisms affects transcriptional activity and may contribute to osteoarthritis genetic susceptibility.
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Structural and functional-annotation of an equine whole genome oligoarray Lauren A Bright, Shane C Burgess, Bhanu Chowdhary, Cyprianna E Swiderski, Fiona M McCarthy BMC Bioinformatics 2009, 10(Suppl 11):S8 (8 October 2009) |
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Osteoarthritis associated with estrogen deficiency Jorge A Roman-Blas, Santos CastaƱeda, Raquel Largo, Gabriel Herrero-Beaumont Arthritis Research & Therapy 2009, 11:241 (21 September 2009) |
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Cartilage homeostasis in health and rheumatic diseases Mary B Goldring, Kenneth B Marcu Arthritis Research & Therapy 2009, 11:224 (19 May 2009) This article is part of a collection on The Scientific Basis of... |
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Circulating RANKL is inversely related to RANKL mRNA levels in bone in osteoarthritic males David Findlay, Mellick Chehade, Helen Tsangari, Susan Neale, Shelley Hay, Blair Hopwood, Susan Pannach, Peter O'Loughlin, Nicola Fazzalari Arthritis Research & Therapy 2008, 10:R2 (8 January 2008) |