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Highly Accessed Letter

Is fibromyalgia a cardiovascular disease? A comment on Martinez-Lavin's review 'Stress, the stress response system, and fibromyalgia'

Francisco Hélder C Félix1* and Juvenia Bezerra Fontenele2

Author Affiliations

1 Department of Biophysiology and Pharmacology, Faculdade de Medicina de Juazeiro do Norte, Juazeiro do Norte, CE, Brazil

2 Faculdade Católica Rainha do Sertão, Quixadá, CE, Brazil

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Arthritis Research & Therapy 2007, 9:404  doi:10.1186/ar2296


See related review by Martinez-Lavin, http://arthritis-research.com/content/9/4/216, related editorial by Eisinger, http://arthritis-research.com/content/9/4/105, related letter by Martinez and Cassol, http://arthritis-research.com/content/10/6/408, and related response by Eisinger, http://arthritis-research.com/content/10/6/409

Published: 31 October 2007

First paragraph (this article has no abstract)

Fibromyalgia syndrome (FMS) is a mysterious condition with uncertain physiopathogenesis. Despite its hermeneutic problems, FMS and related afflictions are responsible for the majority of family medicine and rheumatological medical office appointments. In spite of the skepticism of some, it seems that the medical science community has accepted FMS as a valid, unique clinical diagnosis and the main theory explaining it (the central sensitization model (CSM)) may relate to many chronic pain states.