Table 1

The five main groups of matrix metalloproteinases

Group

MMPs


Collagenases

MMP-1 (collagenase-1), MMP-8 (collagenase-2),

MMP-13 (collagenase-3),

MMP-18 (collagenase-4)

Gelatinases

MMP-2 (gelatinases A), MMP-9 (gelatinases B)

Stromelysins

MMP-3 (stromelysin-1), MMP-10 (stromelysin-2),

MMP-11 (stromelysin-3)

Matrilysins

MMP-7, MMP-26

MT MMPs

MMP-14 (MT1-MMP), MMP-15 (MT2-MMP),

MMP-16 (MT3-MMP), MMP-17 (MT4-MMP),

MMP-24 (MT5-MMP), MMP-25 (MT6-MMP)


MMP, matrix metalloproteinase; MT, membrane type.

Rengel et al. Arthritis Research & Therapy 2007 9:221   doi:10.1186/ar2304