|
The five main groups of matrix metalloproteinases |
|
| Group |
MMPs |
|
|
|
| Collagenases |
MMP-1 (collagenase-1), MMP-8 (collagenase-2), |
| MMP-13 (collagenase-3), |
|
| MMP-18 (collagenase-4) |
|
| Gelatinases |
MMP-2 (gelatinases A), MMP-9 (gelatinases B) |
| Stromelysins |
MMP-3 (stromelysin-1), MMP-10 (stromelysin-2), |
| MMP-11 (stromelysin-3) |
|
| Matrilysins |
MMP-7, MMP-26 |
| MT MMPs |
MMP-14 (MT1-MMP), MMP-15 (MT2-MMP), |
| MMP-16 (MT3-MMP), MMP-17 (MT4-MMP), |
|
| MMP-24 (MT5-MMP), MMP-25 (MT6-MMP) |
|
|
MMP, matrix metalloproteinase; MT, membrane type. | |
Rengel et al. Arthritis Research & Therapy 2007 9:221 doi:10.1186/ar2304 |
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