Table 3 |
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|
Risk factors for hand bone loss in a multivariate linear regression model |
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|
DXA-BMD hand percentage change |
DXR-BMD hand percentage change |
DXR-MCI percentage change |
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|
|
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|
B (standard error) |
P value |
B (standard error) |
P value |
B (standard error) |
P value |
|
|
|
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|
Disease activity score including 28 joints |
0.09 (0.25) |
0.73 |
-0.47 (0.16) |
0.003 |
-0.47 (0.18) |
0.009 |
|
Disease duration <3 years |
-2.84 (0.88) |
0.001 |
0.46 (0.55) |
0.40 |
0.45 (0.63) |
0.47 |
|
Baseline BMD (g/cm2)/MCI |
-9.70 (5.01) |
0.05 |
-3.80 (2.51) |
0.13 |
-5.79 (2.81) |
0.04 |
|
Prednisolone during 2-year follow-up (no/yes) |
0.44 (0.69) |
0.53 |
-0.03 (0.43) |
0.95 |
-0.41 (0.49) |
0.40 |
|
Ever disease-modifying antirheumatic drug user (no/yes) |
-0.31 (0.90) |
0.73 |
-0.58 (0.55) |
0.30 |
-0.56 (0.63) |
0.38 |
|
Ever antiresorptive osteoporosis treatment user (no/yes) |
0.78 (0.70) |
0.27 |
0.03 (0.42) |
0.95 |
-0.05 (0.47) |
0.91 |
|
R2 |
0.11 |
0.05 |
0.06 |
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|
|
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|
B values are unstandardized coefficients. Age, gender, rheumatoid factor and the Modified Health Questionnaire were also tested, but did not influence the results. DXA, dual-energy X-ray absorptiometry; DXR, digital X-ray radiogrammetry; BMD, bone mineral density; MCI, metacarpal cortical index. |
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|
Hoff et al. Arthritis Research & Therapy 2007 9:R81 doi:10.1186/ar2280 |
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