Table 4 |
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|
Body composition and metabolic outcomes in rheumatoid arthritis patients and control subjects |
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|
Variables |
Rheumatoid arthritis (n = 7) |
Controls (n = 10) |
P value |
|
|
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|
Body mass index (kg/m2) |
26.9 ± 0.9 |
27.8 ± 0.9 |
NS |
|
Total lean body mass (kg) |
40.3 ± 1.1 |
46.1 ± 1.6 |
0.019 |
|
Lean body mass, both arms (kg) |
3.9 ± 0.3 |
4.6 ± 0.2 |
0.03 |
|
Lean body mass, both legs (kg) |
12.5 ± 0.4 |
15.4 ± 0.7 |
0.01 |
|
Total body fat mass (kg) |
23.7 ± 0.8 |
25.8 ± 1.5 |
NS |
|
Body fat (percentage) |
35.9 ± 1.1 |
34.6 ± 1.0 |
NS |
|
Bone mineral density (g/cm2)a |
|||
|
Femoral neck |
0.85 ± 0.03 |
0.82 ± 0.05 |
NS |
|
Trochanter |
0.69 ± 0.03 |
0.75 ± 0.05 |
NS |
|
Ward's area |
0.74 ± 0.03 |
0.74 ± 0.06 |
NS |
|
Lumbar spine (L2-L4) |
0.790 ± 0.03 |
0.81 ± 0.04 |
NS |
|
Distal radius |
0.68 ± 0.01 |
0.72 ± 0.02 |
NS |
|
Serum creatinine (mg/dl) |
0.57 ± 0.05 |
0.79 ± 0.02 |
<0.001 |
|
Fasting blood glucose (mg/dl) |
90.6 ± 1.9 |
91.7 ± 2.2 |
NS |
|
Fasting insulin (μU/liter) |
11.20 ± 3.60 |
7.40 ± 0.70 |
NS |
|
Quantitative Insulin Sensitivity Check Index |
0.35 ± 0.01 |
0.36 ± 0.01 |
NS |
|
Total cholesterol (mg/dl) |
156 ± 13 |
198 ± 13 |
0.046 |
|
Low-density lipoprotein cholesterol (mg/dl) |
96.6 ± 11.2 |
124.4 ± 13.3 |
NS |
|
High-density lipoprotein cholesterol (mg/dl) |
47.90 ± 5.30 |
57.7 ± 4.2 |
NS |
|
Triglycerides (mg/dl) |
97.6 ± 9.2 |
109.3 ± 11.5 |
NS |
|
|
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|
Values are presented as mean ± standard error. P value indicates the significance of the difference in each parameter value between patients and control subjects. aOne patient with rheumatoid arthritis was removed from the bone mineral density analysis because of her diagnosis of osteosclerosis. NS, not significant (p > 0.10). |
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|
Blackman et al. Arthritis Research & Therapy 2007 9:R73 doi:10.1186/ar2271 |
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