Figure 2.

A model for dendritic cell presentation of citrullinated self-antigenic peptides, and the development of chronic autoimmune inflammatory disease of joint and vascular tissues. anti-CCP, anticyclic citrullinated peptide; DC, dendritic cells; EC, endothelial cells; FDC, follicular dendritic cells; MΦ, macrophages; ox-LDL, oxidized low-density lipoprotein; RF, rheumatoid factor.