Table 2

Controlled studies of stress testing using the tilt table or heart rate variability analysis in patients with fibromyalgia

Reference

Type of stress test

Number of patients

Number of controls

Main conclusion


Martinez-Lavin and colleagues, 1997 [18]

Active orthostatic stress

19

19

Orthostatic sympathetic derangement

Bou-Holaigah and colleagues, 1997 [19]

Head-up tilt table test

20 (17 female)

20 (18 female)

Hypotension in 60% of patients (0% in controls)

Raj and colleagues, 2000 [13]

Head-up tilt table test

17

14

Positive test in 64% of patients and 21 controls

Naschitz and colleagues, 2001 [20]

'Discriminant score' during head-up tilt table test

38 (67% female)

30 with chronic fatigue syndrome (58% female), 37 normal (65% female)

Discriminant score different in fibromyalgia versus chronic fatigue syndrome

Friederich and colleagues, 2005 [21]

Mental stress, passive orthostatism

28

15

Less sympathetic activation

Furlan and colleagues, 2005 [16]

Head-up tilt table test, muscular sympathetic nerve activity

16 (15 female)

16 (15 female)

Decreased sympathetic response


Martinez-Lavin Arthritis Research & Therapy 2007 9:216   doi:10.1186/ar2146