Table 1 |
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|
Genotype frequencies of the interferon induced with helicase domain 1 A946T polymorphism |
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|
Genotype frequency |
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|
|
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|
GG |
AG |
AA |
|
|
|
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|
Rheumatoid arthritis |
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|
Patients |
126 (13.7%) |
446 (48.5%) |
348 (37.8%) |
|
Controls |
144 (15.5%) |
450 (48.4%) |
335 (36.1%) |
|
Odds ratio (95% confidence interval) |
0.8 (0.6–1.1) |
0.9 (0.8–1.2) |
|
|
P value |
0.2 |
0.6 |
|
|
Rheumatoid factor |
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|
Positive |
76 (13.1%) |
281 (48.5%) |
222 (38.3%) |
|
Negative |
40 (15.2%) |
126 (47.9%) |
97 (36.9%) |
|
Odds ratio (95% confidence interval) |
0.8 (0.5–1.3) |
1.0 (0.7–1.4) |
|
|
P value |
0.4 |
0.9 |
|
|
Cyclic citrullinated peptide |
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|
Positive |
87 (13.1%) |
328 (49.2%) |
251 (37.7%) |
|
Negative |
31 (15.1%) |
99 (48.3%) |
75 (36.6%) |
|
Odds ratio (95% confidence interval) |
0.8 (0.5–1.4) |
1.0 (0.7–1.4) |
|
|
P value |
0.5 |
1.0 |
|
|
Larsen score |
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|
Median |
36.0 (13.4%) |
27.5 (48.3%) |
27.0 (38.3%) |
|
P value |
0.2 |
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|
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|
We assumed a multiplicative inheritance model by performing logistic regression. The model with the largest log-likelihood ratio was chosen as the one that best represented the mode of inheritance of the data. |
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|
Marinou et al. Arthritis Research & Therapy 2007 9:R40 doi:10.1186/ar2179 |
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