Table 1

Clinical summary of the 10 patients studied and their response to treatment
Patient	Clinical presentation	Affected joints	Serum uric acid (normal range, 160–390 μmol/l)	Serum creatinine (normal range, 44–80 μmol/l)	Hypouricemic treatment	Effect of anakinra (hours)	Patient assessment of improvement in pain (%)

Case 1 (female, 72 years old)	Chronic tophaceous gout, renal stones	Fingers, toes	637	79	Uricase	36	70
Case 2 (male, 70 years old)	Chronic tophaceous gout	Ankle, toes	564	202	Allopurinol	24	90
Case 3 (male, 72 years old)	Acute gout	Knee, ankle, foot	482	121	Allopurinol	24	90
Case 4 (male, 51 years old)	Acute gout	Ankle, toe	396	84	Allopurinol	24	100
Case 5 (male, 40 years old)	Acute gout	Ankle, toe	322	113	Allopurinol	36	100
Case 6 (female, 72 years old)	Acute gout	Feet, toe	572	72	None	36	80
Case 7 (male, 76 years old)	Acute gout	Ankle, foot	338	79	None	36	100
Case 8 (male, 70 years old)	Acute gout	Wrist, elbow, hand	779	406	None	48	50
Case 9 (male, 53 years old)	Chronic tophaceous gout	Elbow, finger, foot, ankle	660	84	Allopurinol	48	50
Case 10 (male, 38 years old)	Acute gout	Wrist, finger	540	84	None	24	60

So et al. Arthritis Research & Therapy 2007 9:R28 doi:10.1186/ar2143