Table 1 |
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|
Characteristics of subjects with and without baseline medial meniscal extrusion |
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| Characteristic |
Meniscal extrusion at baseline |
P value |
|
|
|
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| Negative (n = 273) |
Positive (n = 21) |
||
|
|
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| Age (years) |
45.0 (6.6) |
47.2 (5.4) |
0.148 |
| Sex (female [%]) |
59 |
43 |
0.150* |
| Family history of OA (positive [%]) |
45 |
57 |
0.284* |
| Height (cm) |
169.0 (8.5) |
172.1 (8.2) |
0.102 |
| Weight (kg) |
76.6 (14.6) |
92.7 (21.5) |
< 0.001 |
| BMI (kg/m2) |
26.8 (4.5) |
31.3 (7.0) |
< 0.001 |
| Knee pain (%) |
33 |
38 |
0.665* |
| Obese (%) |
18 |
52 |
< 0.001* |
| Past knee injury (%) |
19 |
38 |
0.037* |
| Medial tibial cartilage volume (ml) |
2.2 (0.5) |
2.4 (0.5) |
0.051 |
| Lateral tibial cartilage volume (ml) |
2.6 (0.7) |
2.7 (0.6) |
0.408 |
| Medial femoral cartilage volume (ml) |
4.6 (1.3) |
4.7 (1.0) |
0.632 |
| Lateral femoral cartilage volume (ml) |
4.7 (1.3) |
5.1 (1.0) |
0.280 |
| Medial tibial bone area (cm2) |
17.3 (2.6) |
19.8 (3.8) |
< 0.001 |
| Lateral tibial bone area (cm2) |
11.9 (2.0) |
13.5 (2.5) |
0.001 |
| Medial tibiofemoral cartilage defect (0–8) |
2.0 (0.6) |
3.1 (1.4) |
< 0.001 |
| Lateral tibiofemoral cartilage defect (0–8) |
2.0 (0.7) |
2.1 (0.7) |
0.550 |
| Any radiographic osteoarthritis (%) |
15 |
52 |
< 0.001* |
| Medial joint space narrowing (%) |
13 |
38 |
0.001* |
| Medial osteophytes (%) |
4 |
43 |
< 0.001* |
| Lateral joint space narrowing (%) |
3 |
5 |
0.737* |
| Lateral osteophytes (%) |
3 |
14 |
< 0.001* |
| Change in medial tibial cartilage volume (%) |
-2.4 (4.1) |
-4.7 (4.4) |
0.015 |
| Change in lateral tibial cartilage volume (%) |
-1.5 (3.4) |
-1.6 (3.8) |
0.860 |
| Change in medial femoral cartilage volume (%) |
-3.3 (2.6) |
-4.1 (3.9) |
0.278 |
| Change in lateral femoral cartilage volume (%) |
-3.3 (2.5) |
-3.5 (3.1) |
0.662 |
| Change in medial tibial bone area (%) |
+0.7 (1.8) |
+0.2 (1.7) |
0.258 |
| Change in lateral tibial bone area (%) |
+0.3 (2.8) |
+0.5 (2.4) |
0.781 |
| Change in medial tibiofemoral cartilage defect |
-0.07 (0.86) |
0.29 (1.06) |
0.074 |
| Change in lateral tibiofemoral cartilage defect |
-0.02 (0.81) |
0.50 (1.20) |
0.007 |
|
|
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|
Values are expressed as mean (standard deviation), except for percentage. *χ2 test; all others t-test. BMI, body mass index; OA, osteoarthritis. |
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|
Ding et al. Arthritis Research & Therapy 2007 9:R21 doi:10.1186/ar2132 |
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