Table 1 |
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|
Concentration of IL-6 and PGE2 in supernatants from cultured FLS cells and co-cultures from FLS cells and DRG neurones |
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|
PGE2 (ng/ml) |
IL-6 (ng/ml) |
|
|
|
||
|
DRG neurones |
ND |
ND |
|
FLS cells, normal knee joints |
4.8 ± 2.1 |
10.6 ± 2.2 |
|
FLS cells, acutely inflamed knee joints |
28.6 ± 5.2 |
22.0 ± 4.2 |
|
FLS cells, chronically inflamed knee joints |
92.9 ± 23.4 |
NM |
|
DRG neurones + FLS cells, normal knee joints |
11.7 ± 3.1 |
12.8 ± 2.0 |
|
DRG neurones + FLS cells, acutely inflamed joints |
39.0 ± 4.1 |
26.0 ± 3.9 |
|
DRG neurones + FLS cells, chronically inflamed joints |
75.7 ± 18.5 |
NM |
|
|
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|
DRG, dorsal root ganglion; FLS, fibroblast-like synovial; IL, interleukin; ND, not detected; NM, not measured; PGE2, prostaglandin E2. |
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|
von Banchet et al. Arthritis Research & Therapy 2007 9:R6 doi:10.1186/ar2112 |
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