Table 1

Surface antigens commonly identified during isolation of mesenchymal stem cells (MSCs)


Number of populations reported with specified antigen levelsb





Human MSCsc
 Murine MSCsc



Marker type
 Surface antigena
 +
 +/-
 -
 +
 +/-
 -
 References
Positive
 Stro-1
 7
 1
 2
 0
 0
 0
 4–7,66,82–84

CD13
 5
 0
 0
 1
 0
 1
 2,12,84–87,89–90

CD29
 5
 0
 0
 11
 0
 0
 2,12,63,84–87,90

CD44
 11
 0
 1
 10
 1
 0
 2,63,82,84–87,90–91

CD73
 5
 0
 0
 0
 0
 0
 2,10,83–85

CD105
 7
 0
 0
 1
 0
 0
 2,10,12,83–87

CD106
 4
 0
 2
 4
 1
 0
 2,5,83–84,86–89
Negative
 CD11b
 0
 0
 3
 0
 1
 5
 2,82,86–88,90

CD31
 0
 3
 10
 0
 0
 6
 2,82,84–91

CD34
 1
 1
 10
 5
 6
 3
 2,12,63,82,84–89,91

CD45
 0
 0
 11
 0
 0
 6
 2,82,84–91

CD117
 0
 2
 3
 1
 1
 13
 2,63,82,87–90
Variable
 Sca-1
 0
 0
 0
 6
 5
 4
 63,87–88,90

CD10
 6
 0
 5
 0
 1
 0
 82,85–87,89

CD90
 11
 1
 1
 2
 4
 10
 2,12,63,82,84–85,87–91

Flk-1
 2
 1
 1
 0
 0
 5
 82,88–89

aAntigen chosen if tested in at least 4 MSC populations from the 19 papers reviewed; bnumber of MSC populations (isolated from various tissues from human or mouse) reported in these studies to be mostly positive (+), somewhat positive (+/-), or negative (-); cMSCs isolated primarily from bone marrow but also from fat, skin, thymus, kidney, muscle, liver, lung, and placenta.

Kolf et al. Arthritis Research & Therapy 2007 9:204   doi:10.1186/ar2116