Table 1

Surface antigens commonly identified during isolation of mesenchymal stem cells (MSCs)

Number of populations reported with specified antigen levelsb


Human MSCsc

Murine MSCsc



Marker type

Surface antigena

+

+/-

-

+

+/-

-

References


Positive

Stro-1

7

1

2

0

0

0

4–7,66,82–84

CD13

5

0

0

1

0

1

2,12,84–87,89–90

CD29

5

0

0

11

0

0

2,12,63,84–87,90

CD44

11

0

1

10

1

0

2,63,82,84–87,90–91

CD73

5

0

0

0

0

0

2,10,83–85

CD105

7

0

0

1

0

0

2,10,12,83–87

CD106

4

0

2

4

1

0

2,5,83–84,86–89

Negative

CD11b

0

0

3

0

1

5

2,82,86–88,90

CD31

0

3

10

0

0

6

2,82,84–91

CD34

1

1

10

5

6

3

2,12,63,82,84–89,91

CD45

0

0

11

0

0

6

2,82,84–91

CD117

0

2

3

1

1

13

2,63,82,87–90

Variable

Sca-1

0

0

0

6

5

4

63,87–88,90

CD10

6

0

5

0

1

0

82,85–87,89

CD90

11

1

1

2

4

10

2,12,63,82,84–85,87–91

Flk-1

2

1

1

0

0

5

82,88–89


aAntigen chosen if tested in at least 4 MSC populations from the 19 papers reviewed; bnumber of MSC populations (isolated from various tissues from human or mouse) reported in these studies to be mostly positive (+), somewhat positive (+/-), or negative (-); cMSCs isolated primarily from bone marrow but also from fat, skin, thymus, kidney, muscle, liver, lung, and placenta.

Kolf et al. Arthritis Research & Therapy 2007 9:204   doi:10.1186/ar2116