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Cells of the synovium in rheumatoid arthritis. Osteoclasts

Georg Schett

Arthritis Research & Therapy 2007, 9:203 doi:10.1186/ar2110

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Research article   Open Access

Aberrant splicing of the hRasGRP4 transcript and decreased levels of this signaling protein in the peripheral blood mononuclear cells in a subset of patients with rheumatoid arthritis

Toko Hashimoto, Shinsuke Yasuda, Hideyuki Koide, Hiroshi Kataoka, Tetsuya Horita, Tatsuya Atsumi, Takao Koike Arthritis Research & Therapy 2011, 13:R154 (20 September 2011)

Abstract | Full text | PDF | PubMed

Research article   Open Access

Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis

Letizia Penolazzi, Ilaria Lampronti, Monica Borgatti, Mahmud Khan, Margherita Zennaro, Roberta Piva, Roberto Gambari BMC Complementary and Alternative Medicine 2008, 8:59 (30 October 2008)

Abstract | Full text | PDF | PubMed |  Editor’s summary

Extracts of Emblica officinalis fruits induce apoptosis of mature osteoclasts by interfering with the activity of the transcription factor NF-kB without altering osteoclastogenesis, and could provide an alternative therapeutic approach for the treatment of bone loss disorders.

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