|
Genes whose expression showed the greatest change following incubation of chondrocytes with elevated glucosamine alone |
|||
| Genes whose mean RNA levels were reduced >80% relative to untreated control cultures |
|||
|
|
|||
| Anaphase-promoting complex subunit 8 |
Cyclin-dependent kinase inhibitor 3 |
Kinesin-like protein 1 |
Selenium binding protein 2 |
| Bone morphogenetic protein 4 |
Cytoskeleton associated protein 2 |
Kinesin-related protein KRP1 |
Shc SH2-domain binding protein 1 |
| Calmodulin |
DVS27-related protein |
Lactose operon repressora |
Solute carrier family 4, member 4 |
| Carbonic anhydrase 3 |
Dynein, cytoplasmic, intermediate chain 1 |
Microtubule-associated motor KIF4 |
Sphingomyelin phosphodiesterase 3, neutral |
| Cell cycle protein division p55CDC |
ER transmembrane protein Dri 42 |
NAD-dependent 15-hydroxyprostaglandin deshydrogenase |
Testin (TES1/TES2) |
| Cell division cycle 2 homolog A |
Esk splice form 1 |
Neural precursor cell expressed, developmentally downregulated gene 4Aa |
Thymidine kinase 1 |
| Cell proliferation antigen Ki-67 |
Frizzled related protein (sfrp2 gene)a |
Neuropilin |
Topoisomerase (DNA)2 alpha |
| Cell-cycle-dependent 350K nuclear protein |
G2/mitotic-specific cyclin B1a |
NUF2R protein |
Transforming acidic coiled-coil containing protein 3 |
| c-fos-induced growth factor (vascular endothelial growth factor D) |
Glycine amidinotransferase (l-arginine:glycine amidinotransferase) |
Pituitary tumor-transforming 1 |
Ubiquitin conjugating enzyme |
| Chemokine (C–X–C motif) ligand 12a |
Heat shock protein 90 beta |
Polo-like kinase homolog |
Vascular endothelial growth factor D precursor |
| Clathrin light chain A (Lca) |
Hyaluronon mediated motility receptor (RHAMM) |
Protein regulating cytokinesis 1 |
|
| Cyclin B1 |
Insulin-like growth factor binding protein 3 |
Rac GTPase-activating protein 1a |
|
|
|
|||
| Genes whose mean RNA levels were increased more than fivefold relative to untreated controls |
|||
|
|
|||
| Aldose reductase-like protein |
High mobility group AT-hook 1 |
Plasminogen activator inhibitor 2 type a |
Vesicle-associated membrane protein 1 |
| ATP-binding cassette, subfamily G (WHITE), member 1 |
Matrix metalloproteinase 13 |
Smhs 1 protein |
V-maf musculoapaneurotic fibrosarcoma oncogene family protein B |
| CD28 antigen |
Myo-inositol 1-phosphate synthase A1 |
Sodium-coupled ascorbic acid transporter 2 |
|
| FXYD domain containing ion transport regulator 2 |
NADH-ubiquitone oxidoreductase MLRQ subunit |
Solute carrier family 1, member 3 |
|
|
aMultiple probe sets. | |||
Gouze et al. Arthritis Research & Therapy 2006 8:R173 doi:10.1186/ar2082 |
|||