Effect of HGF on IL-4 and TGF-β1 mRNA expression in tight-skin mice. Total RNA was isolated from the skin, spleen, and lung, and IL-4 and TGF-β1 mRNA expression was analyzed by RT-PCR assay. Data represent the mean ± standard deviation from five mice. *p < 0.05. HGF, hepatocyte growth factor; IL, interleukin; TGF, tumor growth factor.
Iwasaki et al. Arthritis Research & Therapy 2006 8:R161 doi:10.1186/ar2068