Figure 2.

Binding of analog peptides to DRB1*0401. IC₅₀ (50% inhibitory concentration) values are the average of two determinations per peptide. Peptides binding to DRB1*0401 with an IC₅₀ of about 1,000 are represented by striped bars (264A, 266D). Peptides binding to DRB1*0401 with an IC₅₀ of 100 or less (comparable to wild-type peptide binding) are represented by white bars.