Table 5 |
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|
Zonal distribution of proteoglycan |
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|
Normalized PG in superficial zonea |
Normalized PG in mid zoneb |
Normalized PG in deep zonec |
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|
|
|
|
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|
Rabbit no. |
Control |
Loaded |
Difference |
Control |
Loaded |
Difference |
Control |
Loaded |
Difference |
|
|
|||||||||
|
1 |
0.14 |
0.20 |
0.06 |
0.06 |
0.29 |
0.23 |
0.03 |
0.11 |
0.08 |
|
2 |
0.05 |
0.01 |
-0.04 |
0.09 |
0.06 |
-0.02 |
0.06 |
0.09 |
0.03 |
|
3 |
0.27 |
0.33 |
0.06 |
0.22 |
0.31 |
0.09 |
0.19 |
0.28 |
0.09 |
|
4 |
0.27 |
0.18 |
-0.08 |
0.13 |
0.19 |
0.05 |
0.07 |
0.14 |
0.07 |
|
5 |
0.18 |
0.17 |
-0.01 |
0.17 |
0.16 |
-0.01 |
0.14 |
0.18 |
0.04 |
|
6 |
0.06 |
0.17 |
0.11 |
0.15 |
0.15 |
0.00 |
0.18 |
0.22 |
0.04 |
|
|
|||||||||
|
Mean |
0.16 |
0.18 |
0.02 |
0.14 |
0.20 |
0.06 |
0.11 |
0.17 |
0.06 |
|
SD |
0.09 |
0.10 |
0.07 |
0.06 |
0.09 |
0.10 |
0.07 |
0.07 |
0.03 |
|
Significanced |
>0.05 |
>0.05 |
0.003 |
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|
|
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|
aSuperficial zone of cartilage is from 0 to 8 μm; bmid zone is from 8 to 53 μm; cdeep zone is from 53 to 100 μm; the zone thicknesses were determined by polarized light microscopy; dsignificance was calculated using the two-tailed, paired Student t test (α = 0.05). PG, proteoglycan; SD, standard deviation. |
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|
Saadat et al. Arthritis Research & Therapy 2006 8:R147 doi:10.1186/ar2040 |
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