Table 3

Saliva and lacrimal measures

Measure
Group
n
Median (interquartile range)
pa

Unstimulated salivary flow (ml/min)
Normal
20
5.5 (4.0–9.5)
0.0009

RA
25
3.0 (1.0–5.0)

Stimulated salivary flow, 15 min (ml/min)
Normal
20
8.0 (3.8–10.5)
0.0005

RA
25
4.0 (1.5–4.5)

Basal salivary NOx (μM)b
Normal
20
46.1 (19.5–71.3)
NS

RA
25
48.8 (31.3–83.4)

Stimulated salivary NOx, 15 min (μM)b
Normal
20
48.1 (26.6–98.7)
NS

RA
25
37.0 (15.7–81.9)

Schirmer's tear test, left (mm)
Normal
19
14.0 (5.0–30.0)
0.025

RA
25
8.0 (2.0–17.5)

Schirmer's tear test, right (mm)
Normal
19
12.0 (5.0–30.0)
0.008

RA
25
5.0 (1.5–10.0)


NOx, nitrite + nitrate; aNS*, not significant; RA, rheumatoid arthritis. aComparing normal and RA; bsaliva collected on the third day of the diet.

Weinberg et al. Arthritis Research & Therapy 2006 8:R140   doi:10.1186/ar2030

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