|
Renal clearance of creatinine and NOx, and fractional excretion of NOx |
||||
| Measure |
Group |
n |
Median (interquartile range) |
p |
|
|
||||
| Creatinine clearance (ml/min) |
Normal |
20 |
84 (74–97) |
NS (0.071) |
| RA |
25 |
99 (82–133) |
||
| NOx clearance (ml/min), 0–24 h |
Normal |
17 |
125(72–209) |
0.004 |
| RA |
23 |
31 (16–73) |
||
| NOx clearance (ml/min), 24–48 h |
Normal |
17 |
69 (38–106) |
0.026 |
| RA |
23 |
38 (20–58) |
||
| NOx clearance (ml/min), 48–72 h |
Normal |
17 |
47 (20–80) |
0.014 |
| RA |
23 |
27 (11–34) |
||
| NOx fractional excretion, 0–24 h |
Normal |
17 |
1.40 (0.78–2.26) |
0.004 |
| RA |
23 |
0.35 (0.19–0.82) |
||
| NOx fractional excretion, 24–48 h |
Normal |
17 |
0.81 (0.48–1.23) |
0.010 |
| RA) |
23 |
0.29 (0.17–0.71) |
||
| NOx fractional excretion, 48–72 h |
Normal |
17 |
0.56 (0.16–0.94) |
0.010 |
| RA |
23 |
0.28 (0.11–0.38) |
||
|
NOx, nitrite + nitrate; NS, not significant (comparing normal and RA); RA, rheumatoid arthritis. | ||||
Weinberg et al. Arthritis Research & Therapy 2006 8:R140 doi:10.1186/ar2030 |
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