Arthritis Research & Therapy | Volume 8 Issue 5

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	Volume 8 Issue 5
	Comment
	Commentary Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al Will Dixon, Alan Silman Arthritis Research & Therapy 2006, 8:111 (11 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Safety concerns on the development of novel therapeutic drugs Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2006, 8:112 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Review
	Review The role of leptin in innate and adaptive immune responses Eiva Bernotiene, Gaby Palmer, Cem Gabay Arthritis Research & Therapy 2006, 8:217 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome Dan Buskila, Piercarlo Sarzi-Puttini Arthritis Research & Therapy 2006, 8:218 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bisphosphonate-associated osteonecrosis of the jaw: the rheumatologist's role Franco Capsoni, Matteo Longhi, Roberto Weinstein Arthritis Research & Therapy 2006, 8:219 (9 October 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Failure of catecholamines to shift T-cell cytokine responses toward a Th2 profile in patients with rheumatoid arthritis Matthias Wahle, Gesine Hanefeld, Stephan Brunn, Rainer H Straub, Ulf Wagner, Andreas Krause, Holm Häntzschel, Christoph GO Baerwald Arthritis Research & Therapy 2006, 8:R138 (6 August 2006) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury Francesco Dell'Accio, Cosimo De Bari, Noha MF El Tawil, Francesca Barone, Thimios A Mitsiadis, John O'Dowd, Costantino Pitzalis Arthritis Research & Therapy 2006, 8:R139 (7 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures J Brice Weinberg, Thomas Lang, William E Wilkinson, David S Pisetsky, E William St Clair Arthritis Research & Therapy 2006, 8:R140 (14 August 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine Igor Popov, Mu Li, Xiufen Zheng, Hongtao San, Xusheng Zhang, Thomas E Ichim, Motohiko Suzuki, Biao Feng, Costin Vladau, Robert Zhong, Bertha Garcia, Gill Strejan, Robert D Inman, Wei-Ping Min Arthritis Research & Therapy 2006, 8:R141 (15 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Antigen-specific immature dendritic cells suppress collagen-induced arthritis in vitro, which may have potential as a tolerogenic vaccine for autoimmune arthritis treatment.
	Research article Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis Jennifer M Milner, Andrew D Rowan, Tim E Cawston, David A Young Arthritis Research & Therapy 2006, 8:R142 (18 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis Heiner Appel, Christoph Loddenkemper, Zarko Grozdanovic, Harald Ebhardt, Marc Dreimann, Axel Hempfing, Harald Stein, Peter Metz-Stavenhagen, Martin Rudwaleit, Joachim Sieper Arthritis Research & Therapy 2006, 8:R143 (22 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study Luis M Amezcua-Guerra, Rashidi Springall, Ricardo Marquez-Velasco, Lorena Gómez-García, Angélica Vargas, Rafael Bojalil Arthritis Research & Therapy 2006, 8:R144 (25 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Fine mapping of genes within the IDDM8 region in rheumatoid arthritis Anne Hinks, Anne Barton, Sally John, Neil Shephard, Jane Worthington Arthritis Research & Therapy 2006, 8:R145 (31 August 2006) Abstract \| Full text \| PDF \| PubMed
	Research article TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells Takashi Ando, Jiro Ichikawa, Masanori Wako, Kyosuke Hatsushika, Yoshiyuki Watanabe, Michitomo Sakuma, Kachio Tasaka, Hideoki Ogawa, Yoshiki Hamada, Hideo Yagita, Atsuhito Nakao Arthritis Research & Therapy 2006, 8:R146 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study Ehsan Saadat, Howard Lan, Sharmila Majumdar, David M Rempel, Karen B King Arthritis Research & Therapy 2006, 8:R147 (6 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Novel IL10 gene family associations with systemic juvenile idiopathic arthritis Mark S Fife, Ana Gutierrez, Emma M Ogilvie, Carmel JW Stock, Jane M Samuel, Wendy Thomson, Lisa F Mack, Cathryn M Lewis, Patricia Woo Arthritis Research & Therapy 2006, 8:R148 (7 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation Jordi Monfort, Natalia Garcia-Giralt, María J López-Armada, Joan C Monllau, Angeles Bonilla, Pere Benito, Francisco J Blanco Arthritis Research & Therapy 2006, 8:R149 (14 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mechanical pressure causes unbalancing of matrix protein ratios and continued synthesis of two metalloproteinase enzymes involved in tissue degradation in osteoarthritic cartilage, which may characterize the pathogenesis of the disease.
	Research article *Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB10401) transgenic mice** Yoshihiko Sakurai, David D Brand, Bo Tang, Edward F Rosloniec, John M Stuart, Andrew H Kang, Linda K Myers Arthritis Research & Therapy 2006, 8:R150 (18 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study Vokko P van Halm, Michael T Nurmohamed, Jos WR Twisk, Ben AC Dijkmans, Alexandre E Voskuyl Arthritis Research & Therapy 2006, 8:R151 (20 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts Yukiko Komano, Toshihiro Nanki, Kenji Hayashida, Ken Taniguchi, Nobuyuki Miyasaka Arthritis Research & Therapy 2006, 8:R152 (21 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis Gurkirpal Singh, Olivia Wu, Peter Langhorne, Rajan Madhok Arthritis Research & Therapy 2006, 8:R153 (22 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary NSAIDs have been shown to be associated with an increased risk of acute myocardial infarctions, suggesting they should be used with caution in those with risk factors for cardiovascular disease.
	Research article Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis James N Jarvis, Howard R Petty, Yuhong Tang, Mark Frank, Philippe A Tessier, Igor Dozmorov, Kaiyu Jiang, Andrei Kindzelski, Yanmin Chen, Craig Cadwell, Mary Turner, Peter Szodoray, Julie L McGhee, Michael Centola Arthritis Research & Therapy 2006, 8:R154 (26 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Neutrophils remain activated in patients with juvenile rheumatoid arthritis (JRA) even when the disease is controlled, and disruptions in gene regulatory networks suggest neutrophils play an essential role in the pathogenesis of disease.
	Research article CD97 neutralisation increases resistance to collagen-induced arthritis in mice Else N Kop, Janik Adriaansen, Tom JM Smeets, Margriet J Vervoordeldonk, René AW van Lier, Jörg Hamann, Paul P Tak Arthritis Research & Therapy 2006, 8:R155 (28 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al. Eric L Matteson, Tim Bongartz, Alex J Sutton, Iain Buchan Arthritis Research & Therapy 2006, 8:404 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Letter Colchicine in acute gouty arthritis: the optimum dose? George I Varughese, Abraham I Varghese Arthritis Research & Therapy 2006, 8:405 (19 September 2006) Abstract \| Full text \| PDF \| PubMed

	Volume 8 Issue 5
	Comment
	Commentary Is there an association between anti-TNF monoclonal antibody therapy in rheumatoid arthritis and risk of malignancy and serious infection? Commentary on the meta-analysis by Bongartz et al Will Dixon, Alan Silman Arthritis Research & Therapy 2006, 8:111 (11 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Commentary Safety concerns on the development of novel therapeutic drugs Caroline Ospelt, Steffen Gay Arthritis Research & Therapy 2006, 8:112 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Review
	Review The role of leptin in innate and adaptive immune responses Eiva Bernotiene, Gaby Palmer, Cem Gabay Arthritis Research & Therapy 2006, 8:217 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Biology and therapy of fibromyalgia. Genetic aspects of fibromyalgia syndrome Dan Buskila, Piercarlo Sarzi-Puttini Arthritis Research & Therapy 2006, 8:218 (28 July 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Bisphosphonate-associated osteonecrosis of the jaw: the rheumatologist's role Franco Capsoni, Matteo Longhi, Roberto Weinstein Arthritis Research & Therapy 2006, 8:219 (9 October 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Failure of catecholamines to shift T-cell cytokine responses toward a Th2 profile in patients with rheumatoid arthritis Matthias Wahle, Gesine Hanefeld, Stephan Brunn, Rainer H Straub, Ulf Wagner, Andreas Krause, Holm Häntzschel, Christoph GO Baerwald Arthritis Research & Therapy 2006, 8:R138 (6 August 2006) Abstract \| Full text \| PDF \| PubMed \| F1000 Biology
	Research article Activation of WNT and BMP signaling in adult human articular cartilage following mechanical injury Francesco Dell'Accio, Cosimo De Bari, Noha MF El Tawil, Francesca Barone, Thimios A Mitsiadis, John O'Dowd, Costantino Pitzalis Arthritis Research & Therapy 2006, 8:R139 (7 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Serum, urinary, and salivary nitric oxide in rheumatoid arthritis: complexities of interpreting nitric oxide measures J Brice Weinberg, Thomas Lang, William E Wilkinson, David S Pisetsky, E William St Clair Arthritis Research & Therapy 2006, 8:R140 (14 August 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Preventing autoimmune arthritis using antigen-specific immature dendritic cells: a novel tolerogenic vaccine Igor Popov, Mu Li, Xiufen Zheng, Hongtao San, Xusheng Zhang, Thomas E Ichim, Motohiko Suzuki, Biao Feng, Costin Vladau, Robert Zhong, Bertha Garcia, Gill Strejan, Robert D Inman, Wei-Ping Min Arthritis Research & Therapy 2006, 8:R141 (15 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Antigen-specific immature dendritic cells suppress collagen-induced arthritis in vitro, which may have potential as a tolerogenic vaccine for autoimmune arthritis treatment.
	Research article Metalloproteinase and inhibitor expression profiling of resorbing cartilage reveals pro-collagenase activation as a critical step for collagenolysis Jennifer M Milner, Andrew D Rowan, Tim E Cawston, David A Young Arthritis Research & Therapy 2006, 8:R142 (18 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Correlation of histopathological findings and magnetic resonance imaging in the spine of patients with ankylosing spondylitis Heiner Appel, Christoph Loddenkemper, Zarko Grozdanovic, Harald Ebhardt, Marc Dreimann, Axel Hempfing, Harald Stein, Peter Metz-Stavenhagen, Martin Rudwaleit, Joachim Sieper Arthritis Research & Therapy 2006, 8:R143 (22 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Presence of antibodies against cyclic citrullinated peptides in patients with 'rhupus': a cross-sectional study Luis M Amezcua-Guerra, Rashidi Springall, Ricardo Marquez-Velasco, Lorena Gómez-García, Angélica Vargas, Rafael Bojalil Arthritis Research & Therapy 2006, 8:R144 (25 August 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Fine mapping of genes within the IDDM8 region in rheumatoid arthritis Anne Hinks, Anne Barton, Sally John, Neil Shephard, Jane Worthington Arthritis Research & Therapy 2006, 8:R145 (31 August 2006) Abstract \| Full text \| PDF \| PubMed
	Research article TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells Takashi Ando, Jiro Ichikawa, Masanori Wako, Kyosuke Hatsushika, Yoshiyuki Watanabe, Michitomo Sakuma, Kachio Tasaka, Hideoki Ogawa, Yoshiki Hamada, Hideo Yagita, Atsuhito Nakao Arthritis Research & Therapy 2006, 8:R146 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Long-term cyclical in vivo loading increases cartilage proteoglycan content in a spatially specific manner: an infrared microspectroscopic imaging and polarized light microscopy study Ehsan Saadat, Howard Lan, Sharmila Majumdar, David M Rempel, Karen B King Arthritis Research & Therapy 2006, 8:R147 (6 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Novel IL10 gene family associations with systemic juvenile idiopathic arthritis Mark S Fife, Ana Gutierrez, Emma M Ogilvie, Carmel JW Stock, Jane M Samuel, Wendy Thomson, Lisa F Mack, Cathryn M Lewis, Patricia Woo Arthritis Research & Therapy 2006, 8:R148 (7 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Decreased metalloproteinase production as a response to mechanical pressure in human cartilage: a mechanism for homeostatic regulation Jordi Monfort, Natalia Garcia-Giralt, María J López-Armada, Joan C Monllau, Angeles Bonilla, Pere Benito, Francisco J Blanco Arthritis Research & Therapy 2006, 8:R149 (14 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Mechanical pressure causes unbalancing of matrix protein ratios and continued synthesis of two metalloproteinase enzymes involved in tissue degradation in osteoarthritic cartilage, which may characterize the pathogenesis of the disease.
	Research article *Analog peptides of type II collagen can suppress arthritis in HLA-DR4 (DRB10401) transgenic mice** Yoshihiko Sakurai, David D Brand, Bo Tang, Edward F Rosloniec, John M Stuart, Andrew H Kang, Linda K Myers Arthritis Research & Therapy 2006, 8:R150 (18 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Disease-modifying antirheumatic drugs are associated with a reduced risk for cardiovascular disease in patients with rheumatoid arthritis: a case control study Vokko P van Halm, Michael T Nurmohamed, Jos WR Twisk, Ben AC Dijkmans, Alexandre E Voskuyl Arthritis Research & Therapy 2006, 8:R151 (20 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Identification of a human peripheral blood monocyte subset that differentiates into osteoclasts Yukiko Komano, Toshihiro Nanki, Kenji Hayashida, Ken Taniguchi, Nobuyuki Miyasaka Arthritis Research & Therapy 2006, 8:R152 (21 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Risk of acute myocardial infarction with nonselective non-steroidal anti-inflammatory drugs: a meta-analysis Gurkirpal Singh, Olivia Wu, Peter Langhorne, Rajan Madhok Arthritis Research & Therapy 2006, 8:R153 (22 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary NSAIDs have been shown to be associated with an increased risk of acute myocardial infarctions, suggesting they should be used with caution in those with risk factors for cardiovascular disease.
	Research article Evidence for chronic, peripheral activation of neutrophils in polyarticular juvenile rheumatoid arthritis James N Jarvis, Howard R Petty, Yuhong Tang, Mark Frank, Philippe A Tessier, Igor Dozmorov, Kaiyu Jiang, Andrei Kindzelski, Yanmin Chen, Craig Cadwell, Mary Turner, Peter Szodoray, Julie L McGhee, Michael Centola Arthritis Research & Therapy 2006, 8:R154 (26 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central \| Editor’s summary Neutrophils remain activated in patients with juvenile rheumatoid arthritis (JRA) even when the disease is controlled, and disruptions in gene regulatory networks suggest neutrophils play an essential role in the pathogenesis of disease.
	Research article CD97 neutralisation increases resistance to collagen-induced arthritis in mice Else N Kop, Janik Adriaansen, Tom JM Smeets, Margriet J Vervoordeldonk, René AW van Lier, Jörg Hamann, Paul P Tak Arthritis Research & Therapy 2006, 8:R155 (28 September 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Correspondence
	Letter Response to commentary by Dixon and Silman on the systematic review and meta-analysis by Bongartz et al. Eric L Matteson, Tim Bongartz, Alex J Sutton, Iain Buchan Arthritis Research & Therapy 2006, 8:404 (1 September 2006) Abstract \| Full text \| PDF \| PubMed
	Letter Colchicine in acute gouty arthritis: the optimum dose? George I Varughese, Abraham I Varghese Arthritis Research & Therapy 2006, 8:405 (19 September 2006) Abstract \| Full text \| PDF \| PubMed

Explore journal

Articles

Volume 8 Issue 5

Comment

Review

Research

Correspondence