Table 3

MHC2TA genotype and allele frequencies in the Austrian and Swedish study populations

Austrian cohort

Swedish cohort [12]

RA patients (n = 362)

Matched controls (n = 351)

Additional controls (n = 1,709)

RA patients (n = 1262)

Matched controls (n = 704)

Additional controls (n = 1,599)

MHC2TA -168 AA genotype

184 (50.8)*

172 (49.0)^†

894 (52.3)^‡

728 (57.7)

449 (63.8)

989 (61.9)

MHC2TA -168 AG genotype

155 (42.8)

142 (40.5)

669 (39.1)

451 (35.7)

221 (31.4)

528 (33.0)

MHC2TA -168 GG genotype

23 (6.4)

37 (10.5)

146 (8.5)

83 (6.6)

34 (4.8)

82 (5.1)

MHC2TA -168G allele frequency

0.278

0.308

0.281

0.244

0.205

0.216

The MHC2TA genotype and allele frequencies of the present study population and the primary report by Swanberg and colleagues [12]. Carriers of a -168G allele were less frequent in the Austrian cohort compared with the Swedish cohort. *Austrian rheumatoid arthritis (RA) patients versus Swedish RA patients, P = 0.02, ^†Austrian matched controls versus Swedish matched controls, P < 0.001, ^‡Austrian additional controls versus Swedish additional controls, P < 0.001.

Yazdani-Biuki et al. Arthritis Research & Therapy 2006 8:R97   doi:10.1186/ar1974