Table 1

Serological features of human and mouse anti-Su sera

IIF

K562 cell extract IP

TnT IP


Sera

GWB foci

100/102-kDa Su

200-kDa Su

hAgo2

Dicer


Human anti-Su (n = 22)

91%

100%

82%

91%

36%

Mouse anti-Su (n = 7)

100%

100%

100%

100%a

0%b

Human anti-GW182 (n = 2)

100%

50%

50%

50%

100%

Human autoimmune non-anti-Su (n = 10)

0%

0%

0%

0%

0%c

Normal human (n = 10)

0%

0%

0%

0%

0%c

Pre-immune mouse (n = 6)

0%

0%

0%

0%c

0%d


an = 5, bn = 2, cn = 4, dn = 1. GWB, GW body; IIF, indirect immunofluorescence of HEp-2 cells; IP, immunoprecipitation; TnT, in vitro transcription and translation.

Jakymiw et al. Arthritis Research & Therapy 2006 8:R87   doi:10.1186/ar1959

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