Table 1

Serological features of human and mouse anti-Su sera

IIF

K562 cell extract IP

TnT IP

Sera

GWB foci

100/102-kDa Su

200-kDa Su

hAgo2

Dicer

Human anti-Su (n = 22)

91%

100%

82%

91%

36%

Mouse anti-Su (n = 7)

100%

100%

100%

100%^a

0%^b

Human anti-GW182 (n = 2)

100%

50%

50%

50%

100%

Human autoimmune non-anti-Su (n = 10)

0%

0%

0%

0%

0%^c

Normal human (n = 10)

0%

0%

0%

0%

0%^c

Pre-immune mouse (n = 6)

0%

0%

0%

0%^c

0%^d

^an = 5, ^bn = 2, ^cn = 4, ^dn = 1. GWB, GW body; IIF, indirect immunofluorescence of HEp-2 cells; IP, immunoprecipitation; TnT, in vitro transcription and translation.

Jakymiw et al. Arthritis Research & Therapy 2006 8:R87   doi:10.1186/ar1959