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Self-reported health conditions and risk of rheumatoid arthritis, Denmark 1998 to 2003 |
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| Women |
Men |
Both genders |
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| Number of patients/controls |
ORa (95% CI) |
Number of patients/controls |
ORa (95% CI) |
ORa (95% CI) |
|
|
|
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| Mononucleosis |
12/24 |
0.74 (0.35 to 1.56) |
3/12 |
0.48 (0.13 to 1.84) |
0.63 (0.33 to 1.20)b |
| Hay feverc |
61/63 |
1.32 (0.89 to 1.97) |
14/36 |
0.56 (0.27 to 1.17) |
1.13 (0.81 to 1.58) |
| Atopic dermatitis |
19/24 |
0.99 (0.51 to 1.90) |
7/10 |
1.46 (0.51 to 4.20) |
1.12 (0.65 to 1.94) |
| Asthmac,d |
24/40 |
0.74 (0.43 to 1.28) |
4/28 |
0.22 (0.07 to 0.67) |
0.58 (0.36 to 0.93)e |
| Stomach or duodenal ulcer |
20/32 |
0.70 (0.38 to 1.27) |
12/30 |
0.70 (0.33 to 1.47) |
0.73 (0.47 to 1.16)b |
| Diarrhea |
49/84 |
0.72 (0.48 to 1.07) |
27/53 |
1.01 (0.58 to 1.75) |
0.81 (0.59 to 1.12) |
| Type I diabetesc |
2/1 |
2.84 (0.22 to 36.05) |
3/6 |
1.15 (0.26 to 5.00) |
1.30 (0.39 to 4.34) |
| Thyroid diseasec |
38/34 |
1.45 (0.87 to 2.40) |
3/2 |
2.32 (0.35 to 15.44) |
1.52 (0.94 to 2.46)b |
| Periodontal disease |
83/118 |
0.95 (0.67 to 1.33) |
41/88 |
0.92 (0.57 to 1.47) |
0.91 (0.70 to 1.19) |
| Urinary tract infection |
171/256 |
0.76 (0.57 to 1.01) |
13/40 |
0.57 (0.28 to 1.14) |
0.73 (0.57 to 0.95)e |
| Cancer |
12/19 |
0.70 (0.33 to 1.49) |
4/2 |
5.51 (0.89 to 34.19) |
1.01 (0.51 to 1.99) |
| Blood transfusion |
51/66 |
0.99 (0.65 to 1.51) |
12/26 |
0.84 (0.39 to 1.79) |
0.98 (0.68 to 1.40) |
| Tonsillectomy, adenoidectomy, appendectomy, or splenectomy |
163/214 |
0.97 (0.73 to 1.29) |
63/124 |
1.00 (0.65 to 1.55) |
0.98 (0.78 to 1.24) |
| Schizophrenia among first-degree relatives |
6/5 |
2.19 (0.62 to 7.77) |
6/6 |
1.77 (0.51 to 6.11) |
2.08 (0.88 to 4.93)b |
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Numbers of patients and controls refer to participants who ever had the health condition in question. aORs represent comparisons between 'ever' versus 'never' (= reference) for each presented disease, with adjustment for birth year, year or pseudo-year of RA diagnosis, and (when combined) gender. bTest for homogeneity 0.05 < p < 0.20. cPhysician-verified diagnosis. dAsthma before age 45 years. eTest for homogeneity p < 0.05. CI, confidence interval; OR, odds ratio. | |||||
Pedersen et al. Arthritis Research & Therapy 2006 8:R133 doi:10.1186/ar2022 |
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