Table 5

Self-reported health conditions and risk of rheumatoid arthritis, Denmark 1998 to 2003

Women

Men

Both genders




Number of patients/controls

ORa (95% CI)

Number of patients/controls

ORa (95% CI)

ORa (95% CI)


Mononucleosis

12/24

0.74 (0.35 to 1.56)

3/12

0.48 (0.13 to 1.84)

0.63 (0.33 to 1.20)b

Hay feverc

61/63

1.32 (0.89 to 1.97)

14/36

0.56 (0.27 to 1.17)

1.13 (0.81 to 1.58)

Atopic dermatitis

19/24

0.99 (0.51 to 1.90)

7/10

1.46 (0.51 to 4.20)

1.12 (0.65 to 1.94)

Asthmac,d

24/40

0.74 (0.43 to 1.28)

4/28

0.22 (0.07 to 0.67)

0.58 (0.36 to 0.93)e

Stomach or duodenal ulcer

20/32

0.70 (0.38 to 1.27)

12/30

0.70 (0.33 to 1.47)

0.73 (0.47 to 1.16)b

Diarrhea

49/84

0.72 (0.48 to 1.07)

27/53

1.01 (0.58 to 1.75)

0.81 (0.59 to 1.12)

Type I diabetesc

2/1

2.84 (0.22 to 36.05)

3/6

1.15 (0.26 to 5.00)

1.30 (0.39 to 4.34)

Thyroid diseasec

38/34

1.45 (0.87 to 2.40)

3/2

2.32 (0.35 to 15.44)

1.52 (0.94 to 2.46)b

Periodontal disease

83/118

0.95 (0.67 to 1.33)

41/88

0.92 (0.57 to 1.47)

0.91 (0.70 to 1.19)

Urinary tract infection

171/256

0.76 (0.57 to 1.01)

13/40

0.57 (0.28 to 1.14)

0.73 (0.57 to 0.95)e

Cancer

12/19

0.70 (0.33 to 1.49)

4/2

5.51 (0.89 to 34.19)

1.01 (0.51 to 1.99)

Blood transfusion

51/66

0.99 (0.65 to 1.51)

12/26

0.84 (0.39 to 1.79)

0.98 (0.68 to 1.40)

Tonsillectomy, adenoidectomy, appendectomy, or splenectomy

163/214

0.97 (0.73 to 1.29)

63/124

1.00 (0.65 to 1.55)

0.98 (0.78 to 1.24)

Schizophrenia among first-degree relatives

6/5

2.19 (0.62 to 7.77)

6/6

1.77 (0.51 to 6.11)

2.08 (0.88 to 4.93)b


Numbers of patients and controls refer to participants who ever had the health condition in question. aORs represent comparisons between 'ever' versus 'never' (= reference) for each presented disease, with adjustment for birth year, year or pseudo-year of RA diagnosis, and (when combined) gender. bTest for homogeneity 0.05 < p < 0.20. cPhysician-verified diagnosis. dAsthma before age 45 years. eTest for homogeneity p < 0.05. CI, confidence interval; OR, odds ratio.

Pedersen et al. Arthritis Research & Therapy 2006 8:R133   doi:10.1186/ar2022

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