Table 2

Radiographic damage among patients with two, one, or no copies of SE alleles stratified according to RF and anti-CCP status

Antibody status

Number of SE alleles

n

Larsen's score (mean ± SEM)

P (SE2 versus SE1 versus SE0)

All

2

266

46.5 ± 2.3

NS

1

393

43.6 ± 1.9

0

168

39.2 ± 2.6

RF positive

2

177

49.5 ± 2.9

NS

1

253

49.4 ± 2.5

0

94

47.0 ± 3.7

RF negative

2

71

39.0 ± 4.3

0.0458^a

1

120

32.3 ± 2.7

0

65

25.9 ± 3.1

CCP positive

2

226

49.1 ± 2.5

NS

1

312

45.7 ± 2.1

0

98

44.3 ± 3.4

CCP negative

2

30

32.0 ± 5.9

NS

1

67

32.3 ± 3.7

0

58

29.2 ± 3.9

Shown is an analysis of radiographic damage among patients with 2 (SE2), 1 (SE1) or no (SE0) copies of SE alleles stratified according to RF and anti-CCP (shortened to CCP) status. ^aBy analysis of variance. anti-CCP, anti-cyclic citrullinated peptide antibody; NS, not significant; RF, rheumatoid factor; SEM, standard error of the mean.

Mewar et al. Arthritis Research & Therapy 2006 8:R128   doi:10.1186/ar2017