Table 1

Radiographic damage in patients stratified for RF and anti-CCP status

Antibody status

n

Larsen's score (mean ± SEM)

P

RF positive

552

49.1 ± 1.7

<0.0001^a

RF negative

268

33.0 ± 1.9

Anti-CCP positive

672

46.9 ± 1.5

<0.0001^a

Anti-CCP negative

159

31.3 ± 2.4

RF positive/CCP positive

493

49.6 ± 1.8

<0.0001^b

RF positive/CCP negative

39

37.6 ± 5.2

RF negative/CCP positive

143

37.2 ± 2.7

RF negative/CCP negative

109

28.0 ± 2.8

Shown is an analysis of radiographic damage, as assessed by modified Larsen's score, in patients stratified for RF and anti-CCP status. ^at-test. ^bComparison of four groups by analysis of variance. anti-CCP, anti-cyclic citrullinated peptide antibody; RF, rheumatoid factor; SEM, standard error of the mean.

Mewar et al. Arthritis Research & Therapy 2006 8:R128   doi:10.1186/ar2017