Table 2

Comparison of sensitivity and specificity of the anti-modified citrullinated vimentin and the anti-cyclic citrullinated peptide test (n = 467)

Cutoff (U/ml)

Sensitivity (% [95% CI])

Specificity (% [95% CI])

Anti-MCV

20.0^a

69.5 (61.9–76.5)

90.8 (86.9–93.8)

19.0^b

70.1 (62.5–77.0)

89.8 (85.8–92.9)

81.5^c

53.7 (45.7–61.5)

98.7 (96.7–99.6)

Anti-CCP2

10.0^a

70.1 (62.5–77.0)

98.7 (96.7–99.6)

^aRecommended by the manufacturer. Cutoff with identical sensitivity^b and specificity^c compared with the anti-CCP2 test, respectively.

anti-CCP2, second-generation anti-cyclic citrullinated peptide; anti-MCV, anti-modified citrullinated vimentin; CI, confidence interval.

Dejaco et al. Arthritis Research & Therapy 2006 8:R119   doi:10.1186/ar2008