Table 1

Time-fold up- or down-expression of genes analyzed by real time PCR in SSc-MVECs versus N-MVECs

Gene name
Time-fold up- or down-expression in SSc-MVECs relative to N-MVECs


KLK9
10.63 (8.26–13.67)

KLK11
53.07 (41.44–67.98)

KLK12
19.02 (11.61–31.17)

PLXNB1
1.90 (1.41–2.13)

DSG2
35.08 (28.23–43.73)

IL8
2.85 (1.82–4.37)

PLAU
2.44 (1.48–3.65)

PTX3
1.58 (1.29–1.87)

CTGF
1.42 (1.34–1.52)


Upward and downward arrows mean up-regulation and down-regulation in microvascular endothelial cells from patients with systemic sclerosis (SSc-MVECs), respectively. N-MVECs, microvascular endothelial cells from normal subjects.

Giusti et al. Arthritis Research & Therapy 2006 8:R115   doi:10.1186/ar2002