Table 1

Identified arthritis-related gene clusters by transcriptome mapping
ID
 Chr.
 Position (Mb)
 n of genes
 * n of total genes
 Included gene families
1
 17
 33
 10
 48
 MHC class II
2
 17
 34
 8
 67
 Complement
3
 17
 35
 2
 40
 MHC class I

17
 33–35
 20
 155
 MHC class II/Complement/MHC class I






4
 11
 81
 3
 10
 CC chemokine ligand
5
 11
 82
 5
 25
 Schlafen
6
 11
 83
 3
 23
 CC chemokine ligand

11
 81–83
 11
 58
 Schlafen/CC chemokine ligand






7
 6
 68
 3
 19
 Immunoglobulin kappa chain
8
 6
 69
 4
 16
 Immunoglobulin kappa chain
9
 6
 70
 2
 13
 Immunoglobulin kappa chain

6
 68–70
 9
 48
 Immunoglobulin kappa chain






10
 12
 112
 4
 8
 Immunoglobulin heavy chain
11
 12
 113
 2
 3
 Immunoglobulin heavy chain

12
 112–113
 6
 11
 Immunoglobulin heavy chain






12
 6
 124
 5
 23
 Complement/C-type lectin superfamily
13
 15
 79
 5
 27
 Colony stimulating factor 2 receptor, beta
14
 19
 11
 5
 32
 Membrane spanning four-domain, subfamily A






15
 2
 165
 4
 32
 -
16
 3
 146
 4
 10
 Guanylate nucleotide binding protein
17
 17
 17
 4
 11
 Formyl peptide receptor
18
 19
 5
 4
 45
 -






19
 1
 75
 3
 15
 -
20
 1
 167
 3
 16
 Selectin
21
 1
 174
 3
 20
 (Fc receptor)
22
 2
 91
 3
 26
 -
23
 2
 129
 3
 18
 -
24
 4
 131
 3
 18
 -
25
 5
 136
 3
 38
 -
26
 7
 3
 3
 28
 Paired-Ig-like receptor
27
 7
 37
 3
 46
 -
28
 7
 39
 3
 29
 Serum amyloid A
29
 7
 120
 3
 30
 -
30
 9
 126
 3
 15
 CC chemokine receptor
31
 11
 70
 3
 30
 -
32
 11
 102
 3
 37
 -
33
 11
 114
 3
 33
 -
34
 11
 117
 3
 23
 -
35
 15
 105
 3
 25
 -
36
 19
 12
 3
 33
 -
37
 X
 63
 3
 40
 -

*Numbers of total genes in the corresponding 1 megabase were obtained from a Mouse Genome Search in The Bioinformatics Analytical Toolkit [20]. CC, Cysteine-Cysteine type; Chr., chromosome; Fc, Fragment crystallizable; ID, identification number; Ig, immunoglobulin; Mb, megabase; MHC, major histocompatibility complex.

Fujikado et al. Arthritis Research & Therapy 2006 8:R100   doi:10.1186/ar1985

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