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Volume 8 Issue 4
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Comment |
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The RNA interference pathway: a new target for autoimmunity
Ger JM Pruijn Arthritis Research & Therapy 2006, 8:110 (22 June 2006)
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Review |
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Biology and therapy of fibromyalgia. New therapies in fibromyalgia
Lesley M Arnold Arthritis Research & Therapy 2006, 8:212 (1 June 2006)
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Scar wars: is TGFβ the phantom menace in scleroderma?
Andrew Leask Arthritis Research & Therapy 2006, 8:213 (9 June 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Aspects of early arthritis. What determines the evolution of early undifferentiated arthritis and rheumatoid arthritis? An update from the Norfolk Arthritis Register
Deborah PM Symmons, Alan J Silman Arthritis Research & Therapy 2006, 8:214 (14 June 2006)
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Human pregnancy safety for agents used to treat rheumatoid arthritis: adequacy of available information and strategies for developing post-marketing data
Christina D Chambers, Zuhre N Tutuncu, Diana Johnson, Kenneth L Jones Arthritis Research & Therapy 2006, 8:215 (14 June 2006)
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Aspects of early arthritis. Definition of disease states in early arthritis: remission versus minimal disease activity
Annette HM van der Helm-van Mil, Ferdinand C Breedveld, Tom WJ Huizinga Arthritis Research & Therapy 2006, 8:216 (3 July 2006)
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Report |
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Correction: Fish oil: what the prescriber needs to know
Leslie G Cleland, Michael J James, Susanna M Proudman Arthritis Research & Therapy 2006, 8:402 (1 June 2006)
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Research |
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Lack of association between mannose-binding lectin gene polymorphisms and juvenile idiopathic arthritis in a Han population from the Hubei province of China
Min Kang, Hong-Wei Wang, Pei-Xuan Cheng, Zun-Dong Yin, Xiao-Ou Li, Hong Shi, Xiu-Fen Hu Arthritis Research & Therapy 2006, 8:R85 (8 May 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Validation of the International Classification of Functioning, Disability and Health (ICF) Core Set for rheumatoid arthritis from the patient perspective using focus groups
Michaela Coenen, Alarcos Cieza, Tanja A Stamm, Edda Amann, Barbara Kollerits, Gerold Stucki Arthritis Research & Therapy 2006, 8:R84 (9 May 2006)
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Local treatment with the selective IκB kinase β inhibitor NEMO-binding domain peptide ameliorates synovial inflammation
Sander W Tas, Margriet J Vervoordeldonk, Najat Hajji, Michael J May, Sankar Ghosh, Paul P Tak Arthritis Research & Therapy 2006, 8:R86 (9 May 2006)
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Editor’s summary
Local small peptide inhibition of a key regulator of synovial inflammation improves established arthritis in an animal model and also prevents pro-inflammatory cytokine production in human rheumatoid arthritis synovial biopsies.
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Autoimmune targeting of key components of RNA interference
Andrew Jakymiw, Keigo Ikeda, Marvin J Fritzler, Westley H Reeves, Minoru Satoh, Edward KL Chan Arthritis Research & Therapy 2006, 8:R87 (9 May 2006)
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Editor’s summary
Autoantibodies common in systemic rheumatic disease recognise key components of the RNA interference pathway which could potentially implicate an innate anti-viral response in the pathogenesis of autoantibody production.
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Interleukin-15 and interferon-γ participate in the cross-talk between natural killer and monocytic cells required for tumour necrosis factor production
Isidoro González-Álvaro, Carmen Domínguez-Jiménez, Ana M Ortiz, Vanessa Núñez-González, Pedro Roda-Navarro, Elena Fernández-Ruiz, David Sancho, Francisco Sánchez-Madrid Arthritis Research & Therapy 2006, 8:R88 (9 May 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Exogenous sphingomyelinase increases collagen and sulphated glycosaminoglycan production by primary articular chondrocytes: an in vitro study
Sophie J Gilbert, Emma J Blain, Pamela Jones, Victor C Duance, Deborah J Mason Arthritis Research & Therapy 2006, 8:R89 (12 May 2006)
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Knee cartilage loss in symptomatic knee osteoarthritis over 4.5 years
Anita E Wluka, Andrew Forbes, Yuanyuan Wang, Fahad Hanna, Graeme Jones, Flavia M Cicuttini Arthritis Research & Therapy 2006, 8:R90 (16 May 2006)
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Human, viral or mutant human IL-10 expressed after local adenovirus-mediated gene transfer are equally effective in ameliorating disease pathology in a rabbit knee model of antigen-induced arthritis
Annahita Keravala, Eric R Lechman, Joan Nash, Zhibao Mi, Paul D Robbins Arthritis Research & Therapy 2006, 8:R91 (16 May 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Inhibition of macropinocytosis blocks antigen presentation of type II collagen in vitro and in vivo in HLA-DR1 transgenic mice
Alexei von Delwig, Catharien MU Hilkens, Daniel M Altmann, Rikard Holmdahl, John D Isaacs, Clifford V Harding, Helen Robertson, Norman McKie, John H Robinson Arthritis Research & Therapy 2006, 8:R93 (16 May 2006)
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Expression of bioactive bone morphogenetic proteins in the subacromial bursa of patients with chronic degeneration of the rotator cuff
Jana Neuwirth, Renée AE Fuhrmann, Amanda Veit, Matthias Aurich, Ilmars Stonâns, Tilo Trommer, Peter Hortschansky, Susanna Chubinskaya, Juergen A Mollenhauer Arthritis Research & Therapy 2006, 8:R92 (23 May 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Inhibition of protein geranylgeranylation induces apoptosis in synovial fibroblasts
Alison M Connor, Stuart Berger, Aru Narendran, Edward C Keystone Arthritis Research & Therapy 2006, 8:R94 (14 June 2006)
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Modulation of granulocyte-endothelium interactions by antileukoproteinase: inhibition of anti-type II collagen antibody-induced leukocyte attachment to the synovial endothelium
Bettina Sehnert, Philip Gierer, Saleh Ibrahim, Anja Kühl, Reinhard Voll, Kutty Nandakumar, Rikard Holmdahl, Rupert Hallmann, Brigitte Vollmar, Harald Burkhardt Arthritis Research & Therapy 2006, 8:R95 (15 June 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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The MHC2TA -168A>G gene polymorphism is not associated with rheumatoid arthritis in Austrian patients
Babak Yazdani-Biuki, Kerstin Brickmann, Klaus Wohlfahrt, Thomas Mueller, Winfried März, Wilfried Renner, Manuela Gutjahr, Uwe Langsenlehner, Peter Krippl, Thomas C Wascher, Bernhard Paulweber, Winfried Graninger, Hans-Peter Brezinschek Arthritis Research & Therapy 2006, 8:R97 (15 June 2006)
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Relaxin and β-estradiol modulate targeted matrix degradation in specific synovial joint fibrocartilages: progesterone prevents matrix loss
Gihan Hashem, Qin Zhang, Takayuki Hayami, Jean Chen, Wei Wang, Sunil Kapila Arthritis Research & Therapy 2006, 8:R98 (19 June 2006)
Abstract | Full text | PDF | PubMed | F1000 Medicine | F1000 Biology
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Alteration of serotonin transporter density and activity in fibromyalgia
Laura Bazzichi, Gino Giannaccini, Laura Betti, Giovanni Mascia, Laura Fabbrini, Paola Italiani, Francesca De Feo, Tiziana Giuliano, Camillo Giacomelli, Alessandra Rossi, Antonio Lucacchini, Stefano Bombardieri Arthritis Research & Therapy 2006, 8:R99 (21 June 2006)
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Transduction of Cu, Zn-superoxide dismutase mediated by an HIV-1 Tat protein basic domain into human chondrocytes
Hyun Kim, Dae Won Kim, Jinseu Park, Soo Choi Arthritis Research & Therapy 2006, 8:R96 (22 June 2006)
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Identification of arthritis-related gene clusters by microarray analysis of two independent mouse models for rheumatoid arthritis
Noriyuki Fujikado, Shinobu Saijo, Yoichiro Iwakura Arthritis Research & Therapy 2006, 8:R100 (28 June 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations
Carlos Lopez-Larrea, Miguel Blanco-Gelaz, Juan Torre-Alonso, Jacome Armas, Beatriz Suarez-Alvarez, Laura Pruneda, Ana Couto, Segundo Gonzalez, Antonio Lopez-Vázquez, Jesus Martinez-Borra Arthritis Research & Therapy 2006, 8:R101 (28 June 2006)
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Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity
Stefan Carlsen, Kutty Nandakumar, Rikard Holmdahl Arthritis Research & Therapy 2006, 8:R102 (3 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Arthritis severity and binding of cartilage-specific antibodies is enhanced in transgenic mice deficient in type IX collagen, highlighting the importance of cartilage stability in preventing attack by pathogenic antibodies.
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Inhibitory effect of ribbon-type NF-κB decoy oligodeoxynucleotides on osteoclast induction and activity in vitro and in vivo
Yasuo Kunugiza, Tetsuya Tomita, Naruya Tomita, Ryuichi Morishita, Hideki Yoshikawa Arthritis Research & Therapy 2006, 8:R103 (3 July 2006)
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NOS2 polymorphisms associated with the susceptibility to pulmonary arterial hypertension with systemic sclerosis: contribution to the transcriptional activity
Yasushi Kawaguchi, Akiko Tochimoto, Masako Hara, Manabu Kawamoto, Tomoko Sugiura, Yasuhiro Katsumata, Jun Okada, Hirobumi Kondo, Mitsuo Okubo, Naoyuki Kamatani Arthritis Research & Therapy 2006, 8:R104 (3 July 2006)
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Gene profiling in white blood cells predicts infliximab responsiveness in rheumatoid arthritis
Thierry Lequerré, Anne-Christine Gauthier-Jauneau, Carine Bansard, Céline Derambure, Martine Hiron, Olivier Vittecoq, Maryvonne Daveau, Othmane Mejjad, Alain Daragon, François Tron, Xavier Le Loët, Jean-Philippe Salier Arthritis Research & Therapy 2006, 8:R105 (3 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Editor’s summary
Gene profiling in peripheral blood mononuclear cells predict a good versus poor response to infliximab efficacy in patients with long-standing and very active rheumatoid arthritis.
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Impairment of chondrocyte biosynthetic activity by exposure to 3-tesla high-field magnetic resonance imaging is temporary
Ilse-Gerlinde Sunk, Siegfried Trattnig, Winfried B Graninger, Love Amoyo, Birgit Tuerk, Carl-Walter Steiner, Josef S Smolen, Klaus Bobacz Arthritis Research & Therapy 2006, 8:R106 (10 July 2006)
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Coexpression and interaction of CXCL10 and CD26 in mesenchymal cells by synergising inflammatory cytokines: CXCL8 and CXCL10 are discriminative markers for autoimmune arthropathies
Paul Proost, Sofie Struyf, Tamara Loos, Mieke Gouwy, Evemie Schutyser, René Conings, Isabelle Ronsse, Marc Parmentier, Bernard Grillet, Ghislain Opdenakker, Jan Balzarini, Jo Van Damme Arthritis Research & Therapy 2006, 8:R107 (17 July 2006)
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Differential expression, function and response to inflammatory stimuli of 11β-hydroxysteroid dehydrogenase type 1 in human fibroblasts: a mechanism for tissue-specific regulation of inflammation
Rowan S Hardy, Andrew Filer, Mark S Cooper, Greg Parsonage, Karim Raza, Debbie L Hardie, Elizabeth H Rabbitt, Paul M Stewart, Christopher D Buckley, Martin Hewison Arthritis Research & Therapy 2006, 8:R108 (17 July 2006)
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Association of FCGR2A and FCGR2A-FCGR3A haplotypes with susceptibility to giant cell arteritis
Ann W Morgan, Jim I Robinson, Jennifer H Barrett, Javier Martin, Amy Walker, Sarah J Babbage, William ER Ollier, Miguel A Gonzalez-Gay, John D Isaacs Arthritis Research & Therapy 2006, 8:R109 (17 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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Autoantibodies against the replication protein A complex in systemic lupus erythematosus and other autoimmune diseases
Yoshioki Yamasaki, Sonali Narain, Liza Hernandez, Tolga Barker, Keigo Ikeda, Mark S Segal, Hanno B Richards, Edward KL Chan, Westley H Reeves, Minoru Satoh Arthritis Research & Therapy 2006, 8:R111 (17 July 2006)
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Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity
Bert Cruyssen, Stijn Van Looy, Bart Wyns, Rene Westhovens, Patrick Durez, Filip Van den Bosch, Herman Mielants, Luc De Clerck, Ann Peretz, Michel Malaise, Leon Verbruggen, Nathan Vastesaeger, Anja Geldhof, Luc Boullart, Filip De Keyser Arthritis Research & Therapy 2006, 8:R112 (17 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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A cell-cycle independent role for p21 in regulating synovial fibroblast migration in rheumatoid arthritis
James M Woods, Karolina Klosowska, Darrin J Spoden, Nataliya G Stumbo, Douglas J Paige, John C Scatizzi, Michael V Volin, Malathi S Rao, Harris Perlman Arthritis Research & Therapy 2006, 8:R113 (17 July 2006)
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Are bone erosions detected by magnetic resonance imaging and ultrasonography true erosions? A comparison with computed tomography in rheumatoid arthritis metacarpophalangeal joints
Uffe Døhn, Bo J Ejbjerg, Michel Court-Payen, Maria Hasselquist, Eva Narvestad, Marcin Szkudlarek, Jakob M Møller, Henrik S Thomsen, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:R110 (18 July 2006)
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Inhibition of anti-tuberculosis T-lymphocyte function with tumour necrosis factor antagonists
Haïfa Hamdi, Xavier Mariette, Véronique Godot, Karin Weldingh, Abdul Hamid, Maria-Victoria Prejean, Gabriel Baron, Marc Lemann, Xavier Puechal, Maxime Breban, Francis Berenbaum, Jean-Charles Delchier, René-Marc Flipo, Bertrand Dautzenberg, Dominique Salmon, Marc Humbert, Dominique Emilie, the RATIO (Recherche sur Anti-TNF et Infections Opportunistes) Study Group Arthritis Research & Therapy 2006, 8:R114 (19 July 2006)
Abstract | Full text | PDF | PubMed | Cited on BioMed Central
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A model of anti-angiogenesis: differential transcriptosome profiling of microvascular endothelial cells from diffuse systemic sclerosis patients
Betti Giusti, Gabriella Fibbi, Francesca Margheri, Simona Serratì, Luciana Rossi, Filippo Poggi, Ilaria Lapini, Alberto Magi, Angela Del Rosso, Marina Cinelli, Serena Guiducci, Bashar Kahaleh, Laura Bazzichi, Stefano Bombardieri, Marco Matucci-Cerinic, Gian Gensini, Mario Del Rosso, Rosanna Abbate Arthritis Research & Therapy 2006, 8:R115 (19 July 2006)
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Colour duplex sonography of temporal arteries before decision for biopsy: a prospective study in 55 patients with suspected giant cell arteritis
Maria Karahaliou, George Vaiopoulos, Spiros Papaspyrou, Meletios A Kanakis, Konstantinos Revenas, Petros P Sfikakis Arthritis Research & Therapy 2006, 8:R116 (19 July 2006)
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Association of the FCRL3 gene with rheumatoid arthritis: a further example of population specificity?
Stephen Eyre, John Bowes, Catherine Potter, Jane Worthington, Anne Barton Arthritis Research & Therapy 2006, 8:R117 (19 July 2006)
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The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus
Ruth Fritsch-Stork, Daniela Müllegger, Karl Skriner, Beatrice Jahn-Schmid, Josef S Smolen, Günter Steiner Arthritis Research & Therapy 2006, 8:R118 (19 July 2006)
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Diagnostic value of antibodies against a modified citrullinated vimentin in rheumatoid arthritis
Christian Dejaco, Werner Klotz, Heike Larcher, Christina Duftner, Michael Schirmer, Manfred Herold Arthritis Research & Therapy 2006, 8:R119 (19 July 2006)
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Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthritis
Karim Raza, Dagmar Scheel-Toellner, Chi-Yeung Lee, Darrell Pilling, S John Curnow, Francesco Falciani, Victor Trevino, Kanta Kumar, Lakhvir K Assi, Janet M Lord, Caroline Gordon, Christopher D Buckley, Mike Salmon Arthritis Research & Therapy 2006, 8:R120 (19 July 2006)
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Psychological pain treatment in fibromyalgia syndrome: efficacy of operant behavioural and cognitive behavioural treatments
Kati Thieme, Herta Flor, Dennis C Turk Arthritis Research & Therapy 2006, 8:R121 (19 July 2006)
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Diagnostic value of anti-human citrullinated fibrinogen ELISA and comparison with four other anti-citrullinated protein assays
Bert Vander Cruyssen, Tineke Cantaert, Leonor Nogueira, Cyril Clavel, Leen De Rycke, Amélie Dendoven, Mireille Sebag, Dieter Deforce, Christian Vincent, Dirk Elewaut, Guy Serre, Filip De Keyser Arthritis Research & Therapy 2006, 8:R122 (19 July 2006)
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Hepatocyte growth factor prevents lupus nephritis in a murine lupus model of chronic graft-versus-host disease
Takanori Kuroiwa, Tsuyoshi Iwasaki, Takehito Imado, Masahiro Sekiguchi, Jiro Fujimoto, Hajime Sano Arthritis Research & Therapy 2006, 8:R123 (19 July 2006)
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Expression profiling of metalloproteinases and their inhibitors in synovium and cartilage
Rose K Davidson, Jasmine G Waters, Lara Kevorkian, Clare Darrah, Adele Cooper, Simon T Donell, Ian M Clark Arthritis Research & Therapy 2006, 8:R124 (19 July 2006)
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A novel approach to measure the contribution of matrix metalloproteinase in the overall net proteolytic activity present in synovial fluids of patients with arthritis
Nathalie Simard, Gilles Boire, Artur J de Brum-Fernandes, Yves St-Pierre Arthritis Research & Therapy 2006, 8:R125 (19 July 2006)
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Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis
Koji Takasugi, Masahiro Yamamura, Mitsuhiro Iwahashi, Fumio Otsuka, Jiro Yamana, Katsue Sunahori, Masanori Kawashima, Masao Yamada, Hirofumi Makino Arthritis Research & Therapy 2006, 8:R126 (19 July 2006)
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Osteoarthritis and nutrition. From nutraceuticals to functional foods: a systematic review of the scientific evidence
Laurent G Ameye, Winnie SS Chee Arthritis Research & Therapy 2006, 8:R127 (19 July 2006)
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Independent associations of anti-cyclic citrullinated peptide antibodies and rheumatoid factor with radiographic severity of rheumatoid arthritis
Devesh Mewar, Annabel Coote, David J Moore, Ioanna Marinou, Jodie Keyworth, Marion C Dickson, Doug S Montgomery, Michael H Binks, Anthony G Wilson Arthritis Research & Therapy 2006, 8:R128 (20 July 2006)
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Epratuzumab (humanised anti-CD22 antibody) in primary Sjögren's syndrome: an open-label phase I/II study
Serge D Steinfeld, Laure Tant, Gerd R Burmester, Nick KW Teoh, William A Wegener, David M Goldenberg, Olivier Pradier Arthritis Research & Therapy 2006, 8:R129 (20 July 2006)
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Statin-induced expression of CD59 on vascular endothelium in hypoxia: a potential mechanism for the anti-inflammatory actions of statins in rheumatoid arthritis
Anne R Kinderlerer, Rivka Steinberg, Michael Johns, Sarah K Harten, Elaine A Lidington, Dorian O Haskard, Patrick H Maxwell, Justin C Mason Arthritis Research & Therapy 2006, 8:R130 (21 July 2006)
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Predictors of infusion reactions during infliximab treatment in patients with arthritis
Meliha C Kapetanovic, Lotta Larsson, Lennart Truedsson, Gunnar Sturfelt, Tore Saxne, Pierre Geborek Arthritis Research & Therapy 2006, 8:R131 (26 July 2006)
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Macrophage migration inhibitory factor: a mediator of matrix metalloproteinase-2 production in rheumatoid arthritis
Angela Pakozdi, Mohammad A Amin, Christian S Haas, Rita J Martinez, G Kenneth Haines, Lanie L Santos, Eric F Morand, John R David, Alisa E Koch Arthritis Research & Therapy 2006, 8:R132 (26 July 2006)
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Environmental risk factors differ between rheumatoid arthritis with and without auto-antibodies against cyclic citrullinated peptides
Merete Pedersen, Søren Jacobsen, Mette Klarlund, Bo V Pedersen, Allan Wiik, Jan Wohlfahrt, Morten Frisch Arthritis Research & Therapy 2006, 8:R133 (27 July 2006)
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Mice expressing HLA-DQ6α8β transgenes develop polychondritis spontaneously
Jennifer L Lamoureux, Jane Buckner, Chella S David, David S Bradley Arthritis Research & Therapy 2006, 8:R134 (27 July 2006)
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Prostaglandin E2 synthesis in cartilage explants under compression: mPGES-1 is a mechanosensitive gene
Marjolaine Gosset, Francis Berenbaum, Arlette Levy, Audrey Pigenet, Sylvie Thirion, Jean-Louis Saffar, Claire Jacques Arthritis Research & Therapy 2006, 8:R135 (27 July 2006)
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Characterisation of the immune response to type I collagen in scleroderma
Kenneth J Warrington, Usha Nair, Laura D Carbone, Andrew H Kang, Arnold E Postlethwaite Arthritis Research & Therapy 2006, 8:R136 (31 July 2006)
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Familial, structural, and environmental correlates of MRI-defined bone marrow lesions: a sibpair study
Guangju Zhai, James Stankovich, Flavia Cicuttini, Changhai Ding, Graeme Jones Arthritis Research & Therapy 2006, 8:R137 (3 August 2006)
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Editor’s summary
Bone marrow lesions, a cause of pain in patients with knee osteoarthritis, have a heritability estimate of 99% and are more common with increasing age, male sex, and increasing BMI.
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Correspondence |
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Replication of association of the D-repeat polymorphism in asporin with osteoarthristis
Shiro Ikegawa, Shingo Kawamura, Atsushi Takahashi, Takahiro Nakamura, Naoyuki Kamatani Arthritis Research & Therapy 2006, 8:403 (29 June 2006)
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