Table 1 |
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Clinical characteristics and lipid profile of patients with early rheumatoid arthritis and controls |
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| Controls (N = 63) |
Patients |
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| Baseline (N = 58) |
Post treatment (N = 56) |
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| Sex (male/female) |
20/43 |
14/44 |
13/43 |
| Age (years) |
58.4 ± 17.7 |
53.6 ± 15.3 |
54.7 ± 14.8 |
| Body mass index (kg/m2) |
25.8 ± 17.7 |
25.5 ± 3.3 |
25.8 ± 3.1 |
| IgM rheumatoid factor (+/-) |
0/0 |
45/13 |
44/13 |
| C-reactive protein (mg/dl) |
2.1 ± 1.3 |
28.15 ± 20.75 |
4.60 ± 4.20a |
| ESR (mm/h) |
5.2 ± 3.1 |
48.0 ± 19.7 |
14.6 ± 8.7a |
| DAS-28 |
- |
5.8 ± 0.9 |
2.7 ± 1.0a |
| TC (mg/dl) |
190.4 ± 33.9 |
216.5 ± 50.3b |
228.1 ± 42.1c |
| LDL-C (mg/dl) |
126.5 ± 31.3 |
141.6 ± 42.3b |
140.4 ± 32.4 |
| HDL-C (mg/dl) |
51.1 ± 7.4 |
47.5 ± 11.82 |
60.7 ± 13.4a |
| NonHDL-C (mg/dl) |
139.3 ± 30.2 |
172.0 ± 46.3b |
167.4 ± 37.4 |
| Triglycerides (mg/dl) |
97.1 ± 28.3 |
133.0 ± 58.2b |
131.5 ± 56.1 |
| TC/HDL-C |
3.7 ± 0.9 |
4.9 ± 1.3b |
3.8 ± 0.8a |
| LDL-C/HDL-C |
2.5 ± 0.8 |
3.0 ± 1.0b |
2.4 ± 0.6a |
| Apolipoprotein B (mg/dl) |
93 ± 19 |
103 ± 28b |
105 ± 30 |
| Apolipoprotein A-I (mg/dl) |
144 ± 23 |
127 ± 27d |
152 ± 22a |
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Values represent the mean ± standard deviation. ap < 0.001 and cp < 0.05 compared to the baseline values; bp < 0.001 and dp < 0.01 compared to the control group. DAS-28, disease activity for 28 joint indices score; ESR, erythrocyte sedimentation rate; LDL-C, low-density lipoprotein cholesterol; HDL-C, high-density lipoprotein cholesterol; TC, total cholesterol. |
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Georgiadis et al. Arthritis Research & Therapy 2006 8:R82 doi:10.1186/ar1952 |
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