Table 3 |
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|
Results of the odds ratio calculation on the global sample (samples A and B combined) |
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|
Genotypes |
Genotype distribution (n [%]) |
Odds ratio |
95% Confidence interval |
|
|
|
||||
|
RA index (n = 200) |
Pseudo-controlsa (n = 600) |
|||
|
|
||||
|
S2/S2 |
14 (7) |
17 (2.8) |
20.5 |
7.1–58.8 |
|
S2/S3P |
36 (18) |
34 (5.7) |
22.2 |
9.9–49.7 |
|
S2/L |
44 (22) |
120 (20) |
5.9 |
2.9–12.2 |
|
S3P/S3P |
15 (7.5) |
31 (5.2) |
8.2 |
3.2–21.2 |
|
S3P/L |
58 (29) |
164 (27.3) |
4.4 |
2.3–8.4 |
|
L/L |
33 (16.5) |
234 (39) |
1 |
- |
|
|
||||
|
Alleles S2, S3P and L are defined according to amino acid sequence at positions 70–74, as described in Table 1. The L alleles are the low-risk alleles S1, S3D and X. The reference genotype is L/L. aPseudo-controls are the three other genotypes that could be formed by the parental genotypes. |
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|
Michou et al. Arthritis Research & Therapy 2006 8:R79 doi:10.1186/ar1949 |
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