Table 2 |
||||
|
Results of the odds ratio calculation on the replication sample (sample B) |
||||
|
Genotypes |
Genotype distribution (n [%]) |
Odds ratio |
95% Confidence interval |
|
|
|
||||
|
RA index (n = 100) |
Pseudo-controlsa (n = 300) |
|||
|
|
||||
|
S2/S2 |
9 (9) |
11 (3.6) |
18.0 |
4.5–71.1 |
|
S2/S3P |
19 (19) |
17 (5.7) |
19.5 |
6.6–57.2 |
|
S2/L |
23 (23) |
63 (21) |
5.3 |
2.0–13.9 |
|
S3P/S3P |
5 (5) |
7 (2.3) |
8.7 |
2.1–36.9 |
|
S3P/L |
25 (25) |
77 (25.7) |
3.1 |
1.4–6.9 |
|
L/L |
19 (19) |
125 (41.7) |
1 |
- |
|
|
||||
|
Alleles S2, S3P and L are defined according to amino acid sequence at positions 70–74, as described in Table 1. The L alleles are the low-risk alleles S1, S3D and X. The reference genotype is L/L. aPseudo-controls are the three other genotypes that could be formed by the parental genotypes. |
||||
|
Michou et al. Arthritis Research & Therapy 2006 8:R79 doi:10.1186/ar1949 |
||||
