Table 3

The muscle strength, disease activity and damage scores, and twitch interpolation results of patients with myositis

QF (MVC) Strength category
Patient number
QF mass-normalised force F/LBM (N/kg)
Activity status
Damage score (0–3)
Twitch status (-/+)

"Not weak"
1
8.83
Inactive
0
-

2
7.17
Active -
1
-

4
5.64
Active -
1
-

5
5.63
Inactive
1
-

6
5.40
Inactive
1
-

3
6.40
Inactive
2
+
"Weak"
7
4.14
Active -
1
-

8
3.97
Active -
1
-

9
3.69
Active
1
-

11
2.82
Active
1
-

12
2.28
Inactive
3
-

14
2.10
Active
1
-

*17
1.30
Active
3
-

*19
0.99
Inactive
3
-

10
3.32
Active
1
+

13
2.11
Active -
2
+

15
1.84
Active -
3
+

16
1.76
Active -
1
+

18
1.00
Active +
2
+

20
0.80
Inactive
3
+

Twenty patients with myositis listed according to their mass-normalised strength and twitch interpolation results, and stratified as "not weak" and "weak" according to their F/LBM results (see text). In general terms, as QF strength decreased, the incidence of positive twitches increased. Cases 17 and 19 had had muscle biopsies within the previous 6 months, and the results showed end-stage disease with severe muscle atrophy and fibrosis. F/LBM, force per units of lean body mass; MVC, maximum voluntary contraction; QF, quadriceps femoris.

Molloy et al. Arthritis Research & Therapy 2006 8:R67   doi:10.1186/ar1935

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