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Non-steroidal anti-inflammatory drugs, corticosteroids and bisphosphonates during lactation |
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| Drug |
Secretion into breast milk |
Effect on nursing infant |
Breastfeeding allowed |
|
|
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| Non-steroidal anti-inflammatory drugs |
In low concentrations |
No adverse effects |
Diclofenac, flufenamic acid, ibuprofen, indomethacin, ketorolac, mefenamic acid, naproxen and piroxicam are compatible with breastfeeding [41-43] |
| Prednisone |
0.025% of maternal dose |
No adverse effects |
Compatible with breastfeeding [84,85] |
| Dexamethasone |
Not studied |
Not known |
Avoid |
| Betamethasone |
Not studied |
Not known |
Avoid |
| Bisphosphonates |
Pamidronate not detected, no reports on other bisphosphonates |
No adverse effect in one case [91] |
Insufficient data. Risk-benefit must be weighed before breastfeeding |
Østensen et al. Arthritis Research & Therapy 2006 8:209 doi:10.1186/ar1957 |
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