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Volume 8 Issue 3
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Comment |
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The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28
Robert Landewé, Désirée van der Heijde Arthritis Research & Therapy 2006, 8:107 (31 March 2006)
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Targeting B cells in systemic lupus erythematosus: not just déjà vu all over again
Robert Eisenberg Arthritis Research & Therapy 2006, 8:108 (15 May 2006)
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Reshaping Cinderella's slipper: the shared epitope hypothesis
Robert Winchester Arthritis Research & Therapy 2006, 8:109 (22 May 2006)
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Review |
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Biology and therapy of fibromyalgia: pain in fibromyalgia syndrome
Roland Staud Arthritis Research & Therapy 2006, 8:208 (24 April 2006)
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Relevance of the stroma and epithelial-mesenchymal transition (EMT) for the rheumatic diseases
Nathan J Zvaifler Arthritis Research & Therapy 2006, 8:210 (9 May 2006)
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Anti-inflammatory and immunosuppressive drugs and reproduction
Monika Østensen, Munther Khamashta, Michael Lockshin, Ann Parke, Antonio Brucato, Howard Carp, Andrea Doria, Raj Rai, Pierluigi Meroni, Irene Cetin, Ronald Derksen, Ware Branch, Mario Motta, Caroline Gordon, Guillermo Ruiz-Irastorza, Arsenio Spinillo, Deborah Friedman, Rolando Cimaz, Andrew Czeizel, Jean Piette, Ricard Cervera, Roger A Levy, Maurizio Clementi, Sara De Carolis, Michelle Petri, Yehuda Shoenfeld, David Faden, Guido Valesini, Angela Tincani Arthritis Research & Therapy 2006, 8:209 (11 May 2006)
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Aspects of early arthritis. Traditional DMARD therapy: is it sufficient?
Klaus P Machold, Valerie PK Nell, Tanja A Stamm, Josef S Smolen Arthritis Research & Therapy 2006, 8:211 (15 May 2006)
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Research |
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Lack of association of a variable number of aspartic acid residues in the asporin gene with osteoarthritis susceptibility: case-control studies in Spanish Caucasians
Julio Rodriguez-Lopez, Manuel Pombo-Suarez, Myriam Liz, Juan J Gomez-Reino, Antonio Gonzalez Arthritis Research & Therapy 2006, 8:R55 (10 March 2006)
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The validity of a rheumatoid arthritis medical records-based index of severity compared with the DAS28
Masayo Sato, Sebastian Schneeweiss, Richard Scranton, Jeffrey N Katz, Michael E Weinblatt, Jerry Avorn, Gladys Ting, Nancy A Shadick, Daniel H Solomon Arthritis Research & Therapy 2006, 8:R57 (14 March 2006)
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Cartilage oligomeric matrix protein is involved in human limb development and in the pathogenesis of osteoarthritis
Sebastian Koelling, Till Clauditz, Matthias Kaste, Nicolai Miosge Arthritis Research & Therapy 2006, 8:R56 (15 March 2006)
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Decrease in expression of bone morphogenetic proteins 4 and 5 in synovial tissue of patients with osteoarthritis and rheumatoid arthritis
Carsten P Bramlage, Thomas Häupl, Christian Kaps, Ute Ungethüm, Veit Krenn, Axel Pruss, Gerhard A Müller, Frank Strutz, Gerd-R Burmester Arthritis Research & Therapy 2006, 8:R58 (15 March 2006)
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Conventional radiography requires a MRI-estimated bone volume loss of 20% to 30% to allow certain detection of bone erosions in rheumatoid arthritis metacarpophalangeal joints
Bo Jannik Ejbjerg, Aage Vestergaard, Søren Jacobsen, Henrik Thomsen, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:R59 (15 March 2006)
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A promoter haplotype of the interleukin-18 gene is associated with juvenile idiopathic arthritis in the Japanese population
Tomoko Sugiura, Nobuaki Maeno, Yasushi Kawaguchi, Syuji Takei, Hiroyuki Imanaka, Yoshifumi Kawano, Hisae Terajima-Ichida, Masako Hara, Naoyuki Kamatani Arthritis Research & Therapy 2006, 8:R60 (17 March 2006)
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The matrix-forming phenotype of cultured human meniscus cells is enhanced after culture with fibroblast growth factor 2 and is further stimulated by hypoxia
Adetola B Adesida, Lisa M Grady, Wasim S Khan, Timothy E Hardingham Arthritis Research & Therapy 2006, 8:R61 (17 March 2006)
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Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production
Manabu Kawamoto, Masayoshi Harigai, Masako Hara, Yasushi Kawaguchi, Katsunari Tezuka, Michi Tanaka, Tomoko Sugiura, Yasuhiro Katsumata, Chikako Fukasawa, Hisae Ichida, Satomi Higami, Naoyuki Kamatani Arthritis Research & Therapy 2006, 8:R62 (22 March 2006)
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Editor’s summary
Inducible co-stimulator (ICOS) is involved in abnormal T cell activation in systemic lupus erythematosus - interruption of the interaction between ICOS and its receptor may prove to have therapeutic benefits.
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IFNGR1 single nucleotide polymorphisms in rheumatoid arthritis
Stefan Mattyasovszky, Alla Skapenko, Joachim R Kalden, Peter E Lipsky, Hendrik Schulze-Koops Arthritis Research & Therapy 2006, 8:R63 (23 March 2006)
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Immune complexes from rheumatoid arthritis synovial fluid induce FcγRIIa dependent and rheumatoid factor correlated production of tumour necrosis factor-α by peripheral blood mononuclear cells
Linda Mathsson, Jon Lampa, Mohammed Mullazehi, Johan Rönnelid Arthritis Research & Therapy 2006, 8:R64 (28 March 2006)
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TGF β-induced cartilage repair is maintained but fibrosis is blocked in the presence of Smad7
Esmeralda N Blaney Davidson, Elly L Vitters, Wim B van den Berg, Peter M van der Kraan Arthritis Research & Therapy 2006, 8:R65 (29 March 2006)
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Clinical and functional remission: even though biologics are superior to conventional DMARDs overall success rates remain low – results from RABBIT, the German biologics register
Joachim Listing, Anja Strangfeld, Rolf Rau, Jörn Kekow, Erika Gromnica-Ihle, Thilo Klopsch, Winfried Demary, Gerd-Rüdiger Burmester, Angela Zink Arthritis Research & Therapy 2006, 8:R66 (5 April 2006)
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Voluntary activation failure is detectable in some myositis patients with persisting quadriceps femoris weakness: an observational study
Catherine B Molloy, Ahmed O Al-Omar, Kathryn T Edge, Robert G Cooper Arthritis Research & Therapy 2006, 8:R67 (10 April 2006)
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The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus
Anthony P Manderson, Francesco Carlucci, Peter J Lachmann, Robert A Lazarus, Richard J Festenstein, H Terence Cook, Mark J Walport, Marina Botto Arthritis Research & Therapy 2006, 8:R68 (10 April 2006)
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Identification and characterization of the carboxy-terminal region of Sip-1, a novel autoantigen in Behçet's disease
Federica Delunardo, Fabrizio Conti, Paola Margutti, Cristiano Alessandri, Roberta Priori, Alessandra Siracusano, Rachele Riganò, Elisabetta Profumo, Guido Valesini, Maurizio Sorice, Elena Ortona Arthritis Research & Therapy 2006, 8:R71 (12 April 2006)
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The S100A8/A9 heterodimer amplifies proinflammatory cytokine production by macrophages via activation of nuclear factor kappa B and p38 mitogen-activated protein kinase in rheumatoid arthritis
Katsue Sunahori, Masahiro Yamamura, Jiro Yamana, Kouji Takasugi, Masanori Kawashima, Hiroshi Yamamoto, Walter J Chazin, Yuichi Nakatani, Satoru Yui, Hirofumi Makino Arthritis Research & Therapy 2006, 8:R69 (13 April 2006)
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The role played by cell-substrate interactions in the pathogenesis of osteoclast-mediated peri-implant osteolysis
Zhenxin Shen, Tania N Crotti, Kevin P McHugh, Kenichiro Matsuzaki, Ellen M Gravallese, Benjamin E Bierbaum, Steven R Goldring Arthritis Research & Therapy 2006, 8:R70 (13 April 2006)
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Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis. Data from the Spanish registry BIOBADASER
Loreto Carmona, Juan J Gómez-Reino, on behalf of the BIOBADASER Group Arthritis Research & Therapy 2006, 8:R72 (18 April 2006)
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Initial clinical trial of epratuzumab (humanized anti-CD22 antibody) for immunotherapy of systemic lupus erythematosus
Thomas Dörner, Joerg Kaufmann, William A Wegener, Nick Teoh, David M Goldenberg, Gerd R Burmester Arthritis Research & Therapy 2006, 8:R74 (21 April 2006)
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Association of PTPN22 1858 single-nucleotide polymorphism with rheumatoid arthritis in a German cohort: higher frequency of the risk allele in male compared to female patients
Matthias Pierer, Sylke Kaltenhäuser, Sybille Arnold, Matthias Wahle, Christoph Baerwald, Holm Häntzschel, Ulf Wagner Arthritis Research & Therapy 2006, 8:R75 (24 April 2006)
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Osteogenic protein 1 in synovial fluid from patients with rheumatoid arthritis or osteoarthritis: relationship with disease and levels of hyaluronan and antigenic keratan sulfate
Susan Chubinskaya, Benjamin S Frank, Margaret Michalska, Bhavna Kumar, Charis A Merrihew, Eugene Thonar, Mary Lenz, Lori Otten, David C Rueger, Joel A Block Arthritis Research & Therapy 2006, 8:R73 (28 April 2006)
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Bone erosions in rheumatoid arthritis can be repaired through reduction in disease activity with conventional disease-modifying antirheumatic drugs
Haruko Ideguchi, Shigeru Ohno, Hideaki Hattori, Akiko Senuma, Yoshiaki Ishigatsubo Arthritis Research & Therapy 2006, 8:R76 (28 April 2006)
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Folate-targeted immunotherapy effectively treats established adjuvant and collagen-induced arthritis
Chrystal M Paulos, Bindu Varghese, William R Widmer, Gert J Breur, Erina Vlashi, Philip S Low Arthritis Research & Therapy 2006, 8:R77 (28 April 2006)
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Cyclooxygenases and prostaglandin E2 receptors in growth plate chondrocytes in vitro and in situ – prostaglandin E2 dependent proliferation of growth plate chondrocytes
Christoph Brochhausen, Pia Neuland, C James Kirkpatrick, Rolf M Nüsing, Günter Klaus Arthritis Research & Therapy 2006, 8:R78 (28 April 2006)
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Validation of the reshaped shared epitope HLA-DRB1 classification in rheumatoid arthritis
Laëtitia Michou, Pascal Croiseau, Elisabeth Petit-Teixeira, Sophie du Montcel, Isabelle Lemaire, Céline Pierlot, José Osorio, Wafa Frigui, Sandra Lasbleiz, Patrick Quillet, Thomas Bardin, Bernard Prum, Françoise Clerget-Darpoux, François Cornélis, the European Consortium on Rheumatoid Arthritis Families Arthritis Research & Therapy 2006, 8:R79 (28 April 2006)
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The new IL-1 family member IL-1F8 stimulates production of inflammatory mediators by synovial fibroblasts and articular chondrocytes
David Magne, Gaby Palmer, Jenny L Barton, Francoise Mézin, Dominique Talabot-Ayer, Sylvette Bas, Trevor Duffy, Marcus Noger, Pierre-Andre Guerne, Martin JH Nicklin, Cem Gabay Arthritis Research & Therapy 2006, 8:R80 (28 April 2006)
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Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus
Michelle Jackson, Yasmeen Ahmad, Ian N Bruce, Beatrice Coupes, Paul EC Brenchley Arthritis Research & Therapy 2006, 8:R81 (28 April 2006)
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Editor’s summary
Low efficiency of activation of transforming growth factor beta-1 is associated with increased risk of cardiovascular disease and may modulate development of atherosclerosis in patients with lupus.
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Atherogenic lipid profile is a feature characteristic of patients with early rheumatoid arthritis: effect of early treatment – a prospective, controlled study
Athanasios N Georgiadis, Eleni C Papavasiliou, Evangelia S Lourida, Yannis Alamanos, Christina Kostara, Alexandros D Tselepis, Alexandros A Drosos Arthritis Research & Therapy 2006, 8:R82 (28 April 2006)
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Clinical and immunological effects of Rituximab in patients with lupus nephritis refractory to conventional therapy: a pilot study
Mónica Vigna-Perez, Berenice Hernández-Castro, Octavio Paredes-Saharopulos, Diana Portales-Pérez, Lourdes Baranda, Carlos Abud-Mendoza, Roberto González-Amaro Arthritis Research & Therapy 2006, 8:R83 (5 May 2006)
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