|
Number of quadrants with bone erosions in finger joints, stratified by imaging modality and combinations thereof |
||||||||||||||
| Joint |
Quadrants with erosions |
Quadrants with no erosions on US, MRI or CR |
Agreement |
Sensitivity |
Specificity |
|||||||||
|
|
|
|
||||||||||||
| US + MRI + CR |
US + MRI |
MRI + RAD |
US + CR |
US only |
MRI only |
CR only |
US versus MRI (%) |
CR versus MRI (%) |
US |
CR |
US |
CR |
||
|
|
||||||||||||||
| MCP 2nd |
10 |
10 |
2 |
1 |
2 |
7 |
3 |
205 |
225(94) |
217(90) |
0.64 |
0.41 |
0.98 |
0.98 |
| Est. |
9 |
8 |
2 |
1 |
1 |
2 |
2 |
55 |
72(90) |
66(82) |
||||
| Early |
1 |
2 |
0 |
0 |
1 |
2 |
0 |
74 |
77(96) |
75(94) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
3 |
1 |
76 |
76(95) |
76(95) |
||||
|
|
||||||||||||||
| MCP 3rd |
7 |
7 |
4 |
1 |
4 |
12 |
2 |
230 |
217(90) |
214 (89) |
0.47 |
0.37 |
0.97 |
0.98 |
| Est. |
6 |
6 |
4 |
1 |
3 |
6 |
2 |
52 |
64(80) |
62 (78) |
||||
| Early |
1 |
1 |
0 |
0 |
1 |
2 |
0 |
75 |
77(96) |
76 (95) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
4 |
0 |
76 |
76(95) |
76 (95) |
||||
|
|
||||||||||||||
| MCP 4th |
5 |
2 |
0 |
1 |
1 |
5 |
0 |
222 |
229 (97) |
227 (96) |
0.58 |
0.42 |
0.99 |
0.99 |
| Est. |
4 |
1 |
0 |
1 |
1 |
5 |
0 |
64 |
69 (91) |
68 (89) |
||||
| Early |
1 |
1 |
0 |
0 |
0 |
0 |
0 |
78 |
80 (100) |
79 (99) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
80 |
80 (100) |
80 (100) |
||||
|
|
||||||||||||||
| MCP 5th |
7 |
1 |
0 |
1 |
3 |
2 |
1 |
221 |
229 (97) |
228 (97) |
0.80 |
0.70 |
0.98 |
0.99 |
| Est. |
6 |
0 |
0 |
1 |
2 |
0 |
0 |
67 |
73 (96) |
73 (96) |
||||
| Early |
1 |
1 |
0 |
0 |
1 |
0 |
1 |
76 |
78 (97) |
77 (96) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
2 |
0 |
78 |
78 (97) |
78 (97) |
||||
|
|
||||||||||||||
| PIP 2nd |
0 |
0 |
0 |
0 |
6 |
1 |
1 |
212 |
212 (96) |
212 (96) |
- |
- |
0.97 |
0.99 |
| Est. |
0 |
0 |
0 |
0 |
5 |
0 |
1 |
54 |
54 (90) |
54 (90) |
||||
| Early |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
79 |
79 (99) |
79 (99) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
79 |
79 (99) |
79 (99) |
||||
|
|
||||||||||||||
| PIP 3rd |
1 |
0 |
0 |
1 |
7 |
1 |
0 |
210 |
211 (96) |
211 (96) |
0.50 |
0.50 |
0.96 |
0.99 |
| Est. |
1 |
0 |
0 |
1 |
6 |
1 |
0 |
51 |
52 (87) |
52 (87) |
||||
| Early |
0 |
0 |
0 |
0 |
1 |
0 |
0 |
79 |
79 (99) |
79 (99) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
80 |
80 (100) |
80 (100) |
||||
|
|
||||||||||||||
| PIP 4th |
0 |
0 |
0 |
0 |
2 |
1 |
1 |
216 |
216 (98) |
216(98) |
- |
- |
0.99 |
0.99 |
| Est. |
0 |
0 |
0 |
0 |
2 |
0 |
1 |
57 |
57 (95) |
57 (95) |
||||
| Early |
0 |
0 |
0 |
0 |
0 |
1 |
0 |
79 |
79 (99) |
79 (99) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
80 |
80 (100) |
80 (100) |
||||
|
|
||||||||||||||
| PIP 5th |
0 |
0 |
0 |
0 |
1 |
0 |
4 |
215 |
215 (98) |
215(98) |
- |
- |
0.99 |
0.98 |
| Est. |
0 |
0 |
0 |
0 |
0 |
0 |
2 |
58 |
58 (97) |
58(97) |
||||
| Early |
0 |
0 |
0 |
0 |
1 |
0 |
2 |
77 |
77 (96) |
77(96) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
0 |
0 |
80 |
80 (100) |
80 (100) |
||||
|
|
||||||||||||||
| Total |
30 |
20 |
6 |
5 |
26 |
29 |
12 |
1,704 |
1,754 (96) |
1,740 (95) |
0.59 |
0.42 |
0.98 |
0.99 |
| Est. |
26 |
15 |
6 |
5 |
20 |
14 |
8 |
458 |
499 (90) |
490 (89) |
||||
| Early |
4 |
5 |
0 |
0 |
6 |
5 |
3 |
617 |
626 (98) |
621 (97) |
||||
| Control |
0 |
0 |
0 |
0 |
0 |
10 |
1 |
629 |
629 (98) |
629 (98) |
||||
|
The following numbers of joints were evaluated (1,832 in total): 240 MCP second, 240 MCP third, 236 MCP fourth, 236 MCP sixth, 220 PIP second, 220 PIP third, 220 PIP fourth, and 220 PIP fifth. All study participants included. CR, conventional radiography; early, early rheumatoid arthritis; Est., established rheumatoid arthritis; MCP, metacarpophalangeal joint; MRI, magnetic resonance imaging; PIP, proximal interphalangeal joint; US, ultrasonography. | ||||||||||||||
Szkudlarek et al. Arthritis Research & Therapy 2006 8:R52 doi:10.1186/ar1904 |
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