Table 1

Number of quadrants with bone erosions in finger joints, stratified by imaging modality and combinations thereof

Joint

Quadrants with erosions

Quadrants with no erosions on US, MRI or CR

Agreement

Sensitivity

Specificity




US + MRI + CR

US + MRI

MRI + RAD

US + CR

US only

MRI only

CR only

US versus MRI (%)

CR versus MRI (%)

US

CR

US

CR


MCP 2nd

10

10

2

1

2

7

3

205

225(94)

217(90)

0.64

0.41

0.98

0.98

Est.

9

8

2

1

1

2

2

55

72(90)

66(82)

Early

1

2

0

0

1

2

0

74

77(96)

75(94)

Control

0

0

0

0

0

3

1

76

76(95)

76(95)


MCP 3rd

7

7

4

1

4

12

2

230

217(90)

214 (89)

0.47

0.37

0.97

0.98

Est.

6

6

4

1

3

6

2

52

64(80)

62 (78)

Early

1

1

0

0

1

2

0

75

77(96)

76 (95)

Control

0

0

0

0

0

4

0

76

76(95)

76 (95)


MCP 4th

5

2

0

1

1

5

0

222

229 (97)

227 (96)

0.58

0.42

0.99

0.99

Est.

4

1

0

1

1

5

0

64

69 (91)

68 (89)

Early

1

1

0

0

0

0

0

78

80 (100)

79 (99)

Control

0

0

0

0

0

0

0

80

80 (100)

80 (100)


MCP 5th

7

1

0

1

3

2

1

221

229 (97)

228 (97)

0.80

0.70

0.98

0.99

Est.

6

0

0

1

2

0

0

67

73 (96)

73 (96)

Early

1

1

0

0

1

0

1

76

78 (97)

77 (96)

Control

0

0

0

0

0

2

0

78

78 (97)

78 (97)


PIP 2nd

0

0

0

0

6

1

1

212

212 (96)

212 (96)

-

-

0.97

0.99

Est.

0

0

0

0

5

0

1

54

54 (90)

54 (90)

Early

0

0

0

0

1

0

0

79

79 (99)

79 (99)

Control

0

0

0

0

0

1

0

79

79 (99)

79 (99)


PIP 3rd

1

0

0

1

7

1

0

210

211 (96)

211 (96)

0.50

0.50

0.96

0.99

Est.

1

0

0

1

6

1

0

51

52 (87)

52 (87)

Early

0

0

0

0

1

0

0

79

79 (99)

79 (99)

Control

0

0

0

0

0

0

0

80

80 (100)

80 (100)


PIP 4th

0

0

0

0

2

1

1

216

216 (98)

216(98)

-

-

0.99

0.99

Est.

0

0

0

0

2

0

1

57

57 (95)

57 (95)

Early

0

0

0

0

0

1

0

79

79 (99)

79 (99)

Control

0

0

0

0

0

0

0

80

80 (100)

80 (100)


PIP 5th

0

0

0

0

1

0

4

215

215 (98)

215(98)

-

-

0.99

0.98

Est.

0

0

0

0

0

0

2

58

58 (97)

58(97)

Early

0

0

0

0

1

0

2

77

77 (96)

77(96)

Control

0

0

0

0

0

0

0

80

80 (100)

80 (100)


Total

30

20

6

5

26

29

12

1,704

1,754 (96)

1,740 (95)

0.59

0.42

0.98

0.99

Est.

26

15

6

5

20

14

8

458

499 (90)

490 (89)

Early

4

5

0

0

6

5

3

617

626 (98)

621 (97)

Control

0

0

0

0

0

10

1

629

629 (98)

629 (98)


The following numbers of joints were evaluated (1,832 in total): 240 MCP second, 240 MCP third, 236 MCP fourth, 236 MCP sixth, 220 PIP second, 220 PIP third, 220 PIP fourth, and 220 PIP fifth. All study participants included. CR, conventional radiography; early, early rheumatoid arthritis; Est., established rheumatoid arthritis; MCP, metacarpophalangeal joint; MRI, magnetic resonance imaging; PIP, proximal interphalangeal joint; US, ultrasonography.

Szkudlarek et al. Arthritis Research & Therapy 2006 8:R52   doi:10.1186/ar1904

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