Table 2

Protein levels of chemokines in plasma and synovial fluid measured in 14 patients with juvenile idiopathic arthritis and 14 age matched healthy control children

Chemokine

Mean levels (pg/ml)

Patients (± SD)

Controls (± SD)

Plasma

Synovial fluid

p¹

Plasma

p²

CCL3

3,158 (± 2,618)

21,035 (± 10,829)

<0.0001

55.2 (± 63.2)

<0.0001

CXCL10

1,297 (± 1,148)

6,451 (± 3,174)

<0.0003

87.8 (± 184.9

<0.001

CCL5

211,096 (± 222,730)

743 (± 675)

<0.006

65,402.1 (± 12,962)

<0.05

¹Comparison of patient plasma to synovial fluid, paired samples. ²Comparison of plasma of patients and controls, unpaired samples.

Pharoah et al. Arthritis Research & Therapy 2006 8:R50   doi:10.1186/ar1913