Table 1

Lupus dendritic cells show a decreased CD80/CD86 ratio ex vivo

Mouse strain

CD80/CD86

p

BALB/c

1.23 ± 0.39

NZM

0.79 ± 0.34

0.006

C57BL/6

1.32 ± 0.35

We calculated CD80/CD86 ratios, dividing the percentage of dendritic cells positive for CD80 by the percentage of dendritic cells positive for CD86 in each mouse (ex vivo) analyzed. Ratios are shown as means ± SD, and the Kruskal-Wallis p value for these ratios is shown.

Colonna et al. Arthritis Research & Therapy 2006 8:R49   doi:10.1186/ar1911