Table 1 |
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|
Severity of arthritis and anti-collagen type II (anti-CII) titers in (NFR/N × B10.Q) × B10.Q female mice and parental strains |
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| Generation |
n |
Day of onset (range)a |
Maximum scoreb |
Anti-CII titers (± standard error) (mg/ml) on day 100 |
|
|
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| F0 NFR/N |
20 |
76.0 (11–102) |
4.0 ± 1 |
1.53 ± 0.37c |
| F0 B10.Q |
19 |
49.5 (12–69) |
4.0 ± 1 |
0.87 ± 0.11 |
| (NFR/N × B10.Q) × B10.Q |
200 |
56.0 (8–105) |
6.0 ± 0.2 |
1.63 ± 0.18 |
|
|
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|
aMedian value on the days of onset when calculated in all arthritic mice in the group on day 100 (maximum–minimum values in the series). bMean ± standard error of the maximum score from all arthritic mice in the respective group. cSignificantly higher than in B10.Q mice (P = 0.02 in Student's unpaired t test). |
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|
Liljander et al. Arthritis Research & Therapy 2006 8:R45 doi:10.1186/ar1901 |
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