Table 1

Typical substrates of p38 mitogen-activated protein (MAP) kinase

Substrate
Reference

Transcription factors
     Activating transcription factor 2 (ATF2)
[119]
     SRF accessory protein 1 (Sap1)
[120]
     C/EBP homologous protein (CHOP)
[121]
     p53
[122]
     Myocyte enhancer factor 2A (MEF2A)
[123]
     Myocyte enhancer factor 2C (MEF2C)
[124]
     CAAT-enhancer binding protein β (C/EBPβ)
[125]
     Nuclear factor of activated T cells p (NFATp)
[74]
     Signal transducers and activators of transcription (STAT4)
[79]
Protein kinases
     MAP kinase-activated protein kinase 2 (MAPKAPK2 or MK2)
[126]
     MAP kinase-activated protein kinase 3 (MK3)
[127]
     MAP kinase interaction protein kinase 1 (MNK1)
[128]
     p38 regulated/activated kinase (PRAK)
[129]
     Mitogen- and stress-activated kinase 1 and 2 (MSK1/2)
[130]

Dodeller and Schulze-Koops Arthritis Research & Therapy 2006 8:205   doi:10.1186/ar1905