Arthritis Research & Therapy | Volume 8 Issue 2

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	Volume 8 Issue 2
	Comment
	Commentary Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk Lawrence Goldkind, Lee S Simon Arthritis Research & Therapy 2006, 8:105 (2 March 2006) Abstract \| Full text \| PDF \| PubMed
	Commentary Usurped SLRPs: novel arthritis biomarkers exposed by catabolism of small leucine-rich proteoglycans? Carl R Flannery Arthritis Research & Therapy 2006, 8:106 (13 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells Francis Dodeller, Hendrik Schulze-Koops Arthritis Research & Therapy 2006, 8:205 (17 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow Jean-Pierre Pelletier, Johanne Martel-Pelletier, Jean-Pierre Raynauld Arthritis Research & Therapy 2006, 8:206 (21 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Magnetic resonance imaging in psoriatic arthritis: a review of the literature Fiona McQueen, Marissa Lassere, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:207 (23 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case–control study Berthold Hoppe, Thomas Häupl, Rudolf Gruber, Holger Kiesewetter, Gerd R Burmester, Abdulgabar Salama, Thomas Dörner Arthritis Research & Therapy 2006, 8:R34 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215] Ralf H Wittenberg, Ernest Schell, Gerhard Krehan, Roland Maeumbaed, Hans Runge, Peter Schlüter, Taiwo OA Fashola, Helen J Thurston, Klaus J Burger, Ulrich Trechsel Arthritis Research & Therapy 2006, 8:R35 (16 January 2006) Abstract \| Full text \| PDF \| PubMed
	Research article The induction of CCN2 by TGFβ1 involves Ets-1 Jonathan P Van Beek, Laura Kennedy, Jason S Rockel, Suzanne M Bernier, Andrew Leask Arthritis Research & Therapy 2006, 8:R36 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase Lei Wei, Xiao-juan Sun, Zhengke Wang, Qian Chen Arthritis Research & Therapy 2006, 8:R37 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Association between microscopic brain damage as indicated by magnetization transfer imaging and anticardiolipin antibodies in neuropsychiatric lupus Stefan CA Steens, Gerlof Bosma, Gerda M Steup-Beekman, Saskia le Cessie, Tom WJ Huizinga, Mark A van Buchem Arthritis Research & Therapy 2006, 8:R38 (16 January 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages Karin Römisch, Frederick W Miller, Bernhard Dobberstein, Stephen High Arthritis Research & Therapy 2006, 8:R39 (26 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis Olivier Meyer, Pascale Nicaise-Roland, Marie Santos, Colette Labarre, Maxime Dougados, Philippe Goupille, Alain Cantagrel, Jean Sibilia, Bernard Combe Arthritis Research & Therapy 2006, 8:R40 (26 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis Allan A Young, Susan McLennan, Margaret M Smith, Susan M Smith, Martin A Cake, Richard A Read, James Melrose, David H Sonnabend, Carl R Flannery, Christopher B Little Arthritis Research & Therapy 2006, 8:R41 (31 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans Begoña Santiago, Françoise Baleux, Guillermo Palao, Irene Gutiérrez-Cañas, Juan C Ramírez, Fernando Arenzana-Seisdedos, José L Pablos Arthritis Research & Therapy 2006, 8:R43 (3 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes Ping Zhu, Ning Lu, Zhan-guo Shi, Jun Zhou, Zhen-biao Wu, Yong Yang, Jin Ding, Zhi-nan Chen Arthritis Research & Therapy 2006, 8:R44 (8 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs Patricia López, Jesús Gómez, Lourdes Mozo, Carmen Gutiérrez, Ana Suárez Arthritis Research & Therapy 2006, 8:R42 (13 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Identification of collagen-induced arthritis loci in aged multiparous female mice Maria Liljander, Mary-Ann Sällström, Sara Andersson, Åsa Andersson, Rikard Holmdahl, Ragnar Mattsson Arthritis Research & Therapy 2006, 8:R45 (14 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology Johan Lindberg, Erik af Klint, Ann-Kristin Ulfgren, André Stark, Tove Andersson, Peter Nilsson, Lars Klareskog, Joakim Lundeberg Arthritis Research & Therapy 2006, 8:R47 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D receptor gene BsmI polymorphisms in Thai patients with systemic lupus erythematosus Wilaiporn Sakulpipatsin, Oravan Verasertniyom, Kanokrat Nantiruj, Kitti Totemchokchyakarn, Porntawee Lertsrisatit, Suchela Janwityanujit Arthritis Research & Therapy 2006, 8:R48 (20 February 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure Theresa Kapral, Tanja Stamm, Klaus P Machold, Karin Montag, Josef S Smolen, Daniel Aletaha Arthritis Research & Therapy 2006, 8:R46 (24 February 2006) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Administering a second course of methotrexate to rheumatoid arthritis sufferers proved beneficial in nearly half of the patients studied, for whom a previous treatment with the drug was ineffective.
	Research article Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus Lucrezia Colonna, Joudy-Ann Dinnall, Debra K Shivers, Lorenza Frisoni, Roberto Caricchio, Stefania Gallucci Arthritis Research & Therapy 2006, 8:R49 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells Daniel S Pharoah, Hemlata Varsani, Richard W Tatham, Katy R Newton, Wilco de Jager, Berent J Prakken, Nigel Klein, Lucy R Wedderburn Arthritis Research & Therapy 2006, 8:R50 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome Marc Ittah, Corinne Miceli-Richard, Jacques- Eric Gottenberg, Frédéric Lavie, Thierry Lazure, Nathalie Ba, Jérémie Sellam, Christine Lepajolec, Xavier Mariette Arthritis Research & Therapy 2006, 8:R51 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Ultrasonography of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic resonance imaging, conventional radiography and clinical examination Marcin Szkudlarek, Mette Klarlund, Eva Narvestad, Michel Court-Payen, Charlotte Strandberg, Karl E Jensen, Henrik S Thomsen, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:R52 (6 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Suppression of inflammation by low-dose methotrexate is mediated by adenosine A_2Areceptor but not A₃receptor activation in thioglycollate-induced peritonitis M Carmen Montesinos, Avani Desai, Bruce N Cronstein Arthritis Research & Therapy 2006, 8:R53 (6 March 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Enhanced expression of mRNA for nuclear factor κB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis Shunsei Hirohata, Yasushi Miura, Tetsuya Tomita, Hideki Yoshikawa, Takahiro Ochi, Nicholas Chiorazzi Arthritis Research & Therapy 2006, 8:R54 (6 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

	Volume 8 Issue 2
	Comment
	Commentary Patients, their doctors, nonsteroidal anti-inflammatory drugs and the perception of risk Lawrence Goldkind, Lee S Simon Arthritis Research & Therapy 2006, 8:105 (2 March 2006) Abstract \| Full text \| PDF \| PubMed
	Commentary Usurped SLRPs: novel arthritis biomarkers exposed by catabolism of small leucine-rich proteoglycans? Carl R Flannery Arthritis Research & Therapy 2006, 8:106 (13 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review
	Review The p38 mitogen-activated protein kinase signaling cascade in CD4 T cells Francis Dodeller, Hendrik Schulze-Koops Arthritis Research & Therapy 2006, 8:205 (17 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Most recent developments in strategies to reduce the progression of structural changes in osteoarthritis: today and tomorrow Jean-Pierre Pelletier, Johanne Martel-Pelletier, Jean-Pierre Raynauld Arthritis Research & Therapy 2006, 8:206 (21 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Review Magnetic resonance imaging in psoriatic arthritis: a review of the literature Fiona McQueen, Marissa Lassere, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:207 (23 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research
	Research article Detailed analysis of the variability of peptidylarginine deiminase type 4 in German patients with rheumatoid arthritis: a case–control study Berthold Hoppe, Thomas Häupl, Rudolf Gruber, Holger Kiesewetter, Gerd R Burmester, Abdulgabar Salama, Thomas Dörner Arthritis Research & Therapy 2006, 8:R34 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article First-dose analgesic effect of the cyclo-oxygenase-2 selective inhibitor lumiracoxib in osteoarthritis of the knee: a randomized, double-blind, placebo-controlled comparison with celecoxib [NCT00267215] Ralf H Wittenberg, Ernest Schell, Gerhard Krehan, Roland Maeumbaed, Hans Runge, Peter Schlüter, Taiwo OA Fashola, Helen J Thurston, Klaus J Burger, Ulrich Trechsel Arthritis Research & Therapy 2006, 8:R35 (16 January 2006) Abstract \| Full text \| PDF \| PubMed
	Research article The induction of CCN2 by TGFβ1 involves Ets-1 Jonathan P Van Beek, Laura Kennedy, Jason S Rockel, Suzanne M Bernier, Andrew Leask Arthritis Research & Therapy 2006, 8:R36 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CD95-induced osteoarthritic chondrocyte apoptosis and necrosis: dependency on p38 mitogen-activated protein kinase Lei Wei, Xiao-juan Sun, Zhengke Wang, Qian Chen Arthritis Research & Therapy 2006, 8:R37 (16 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Association between microscopic brain damage as indicated by magnetization transfer imaging and anticardiolipin antibodies in neuropsychiatric lupus Stefan CA Steens, Gerlof Bosma, Gerda M Steup-Beekman, Saskia le Cessie, Tom WJ Huizinga, Mark A van Buchem Arthritis Research & Therapy 2006, 8:R38 (16 January 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Human autoantibodies against the 54 kDa protein of the signal recognition particle block function at multiple stages Karin Römisch, Frederick W Miller, Bernhard Dobberstein, Stephen High Arthritis Research & Therapy 2006, 8:R39 (26 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Serial determination of cyclic citrullinated peptide autoantibodies predicted five-year radiological outcomes in a prospective cohort of patients with early rheumatoid arthritis Olivier Meyer, Pascale Nicaise-Roland, Marie Santos, Colette Labarre, Maxime Dougados, Philippe Goupille, Alain Cantagrel, Jean Sibilia, Bernard Combe Arthritis Research & Therapy 2006, 8:R40 (26 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Proteoglycan 4 downregulation in a sheep meniscectomy model of early osteoarthritis Allan A Young, Susan McLennan, Margaret M Smith, Susan M Smith, Martin A Cake, Richard A Read, James Melrose, David H Sonnabend, Carl R Flannery, Christopher B Little Arthritis Research & Therapy 2006, 8:R41 (31 January 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CXCL12 is displayed by rheumatoid endothelial cells through its basic amino-terminal motif on heparan sulfate proteoglycans Begoña Santiago, Françoise Baleux, Guillermo Palao, Irene Gutiérrez-Cañas, Juan C Ramírez, Fernando Arenzana-Seisdedos, José L Pablos Arthritis Research & Therapy 2006, 8:R43 (3 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes Ping Zhu, Ning Lu, Zhan-guo Shi, Jun Zhou, Zhen-biao Wu, Yong Yang, Jin Ding, Zhi-nan Chen Arthritis Research & Therapy 2006, 8:R44 (8 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs Patricia López, Jesús Gómez, Lourdes Mozo, Carmen Gutiérrez, Ana Suárez Arthritis Research & Therapy 2006, 8:R42 (13 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Identification of collagen-induced arthritis loci in aged multiparous female mice Maria Liljander, Mary-Ann Sällström, Sara Andersson, Åsa Andersson, Rikard Holmdahl, Ragnar Mattsson Arthritis Research & Therapy 2006, 8:R45 (14 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Variability in synovial inflammation in rheumatoid arthritis investigated by microarray technology Johan Lindberg, Erik af Klint, Ann-Kristin Ulfgren, André Stark, Tove Andersson, Peter Nilsson, Lars Klareskog, Joakim Lundeberg Arthritis Research & Therapy 2006, 8:R47 (16 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Vitamin D receptor gene BsmI polymorphisms in Thai patients with systemic lupus erythematosus Wilaiporn Sakulpipatsin, Oravan Verasertniyom, Kanokrat Nantiruj, Kitti Totemchokchyakarn, Porntawee Lertsrisatit, Suchela Janwityanujit Arthritis Research & Therapy 2006, 8:R48 (20 February 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Methotrexate in rheumatoid arthritis is frequently effective, even if re-employed after a previous failure Theresa Kapral, Tanja Stamm, Klaus P Machold, Karin Montag, Josef S Smolen, Daniel Aletaha Arthritis Research & Therapy 2006, 8:R46 (24 February 2006) Abstract \| Full text \| PDF \| PubMed \| Editor’s summary Administering a second course of methotrexate to rheumatoid arthritis sufferers proved beneficial in nearly half of the patients studied, for whom a previous treatment with the drug was ineffective.
	Research article Abnormal costimulatory phenotype and function of dendritic cells before and after the onset of severe murine lupus Lucrezia Colonna, Joudy-Ann Dinnall, Debra K Shivers, Lorenza Frisoni, Roberto Caricchio, Stefania Gallucci Arthritis Research & Therapy 2006, 8:R49 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Expression of the inflammatory chemokines CCL5, CCL3 and CXCL10 in juvenile idiopathic arthritis, and demonstration of CCL5 production by an atypical subset of CD8+ T cells Daniel S Pharoah, Hemlata Varsani, Richard W Tatham, Katy R Newton, Wilco de Jager, Berent J Prakken, Nigel Klein, Lucy R Wedderburn Arthritis Research & Therapy 2006, 8:R50 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article B cell-activating factor of the tumor necrosis factor family (BAFF) is expressed under stimulation by interferon in salivary gland epithelial cells in primary Sjögren's syndrome Marc Ittah, Corinne Miceli-Richard, Jacques- Eric Gottenberg, Frédéric Lavie, Thierry Lazure, Nathalie Ba, Jérémie Sellam, Christine Lepajolec, Xavier Mariette Arthritis Research & Therapy 2006, 8:R51 (28 February 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Ultrasonography of the metacarpophalangeal and proximal interphalangeal joints in rheumatoid arthritis: a comparison with magnetic resonance imaging, conventional radiography and clinical examination Marcin Szkudlarek, Mette Klarlund, Eva Narvestad, Michel Court-Payen, Charlotte Strandberg, Karl E Jensen, Henrik S Thomsen, Mikkel Østergaard Arthritis Research & Therapy 2006, 8:R52 (6 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central
	Research article Suppression of inflammation by low-dose methotrexate is mediated by adenosine A_2Areceptor but not A₃receptor activation in thioglycollate-induced peritonitis M Carmen Montesinos, Avani Desai, Bruce N Cronstein Arthritis Research & Therapy 2006, 8:R53 (6 March 2006) Abstract \| Full text \| PDF \| PubMed
	Research article Enhanced expression of mRNA for nuclear factor κB1 (p50) in CD34+ cells of the bone marrow in rheumatoid arthritis Shunsei Hirohata, Yasushi Miura, Tetsuya Tomita, Hideki Yoshikawa, Takahiro Ochi, Nicholas Chiorazzi Arthritis Research & Therapy 2006, 8:R54 (6 March 2006) Abstract \| Full text \| PDF \| PubMed \| Cited on BioMed Central

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Volume 8 Issue 2

Comment

Review

Research