|
Genotype frequencies in UK Caucasian and North Indian/Pakistani rheumatoid arthritis patients and healthy controls |
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| Gene |
Genotype |
UK Caucasian |
North Indian/Pakistani |
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|
|
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| Control (n = 129) |
RA (n = 147) |
P |
Nodular RA (n = 37) |
P |
Control (n = 128) |
RA (n = 123) |
P |
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|
|
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| FCGR2A-131 |
RR |
39 (0.31) |
40 (0.28) |
0.81 |
7 (0.19) |
0.36 |
25 (0.19) |
30 (0.25) |
0.15 |
| RH |
59 (0.47) |
72 (0.49) |
21 (0.58) |
66 (0.52) |
48 (0.39) |
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| HH |
28 (0.22) |
34 (0.23) |
8 (0.22) |
37 (0.29) |
44 (0.36) |
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| FCGR3A-158 |
FF |
68 (0.48) |
59 (0.39) |
0.15 |
12 (0.31) |
0.02 |
63 (0.49) |
48 (0.38) |
0.21 |
| FV |
61 (0.43) |
69 (0.46) |
17 (0.45) |
57 (0.44) |
66 (0.52) |
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| VV |
12 (0.09) |
22 (0.15) |
9 (0.24) |
9 (0.07) |
12 (0.10) |
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| FCGR3B-NA |
22 |
48 (0.37) |
55 (0.38) |
0.13 |
16 (0.43) |
0.28 |
49 (0.39) |
47 (0.39) |
0.25 |
| 21 |
72 (0.56) |
71 (0.48) |
16 (0.43) |
45 (0.35) |
53 (0.43) |
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| 11 |
9 (0.07) |
21 (0.14) |
5 (0.14) |
33 (0.26) |
22 (0.18) |
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| FCGR2B-1206 |
GG |
56 (0.48) |
67 (0.46) |
0.96 |
16 (0.43) |
0.19 |
61 (0.48) |
58 (0.47) |
0.98 |
| GA |
50 (0.42) |
63 (0.43) |
13 (0.35) |
54 (0.43) |
54 (0.44) |
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| AA |
12 (0.10) |
16 (0.11) |
8 (0.22) |
11 (0.09) |
11 (0.09) |
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|
Values are expressed as number (%). RA, rheumatoid arthritis. | |||||||||
Morgan et al. Arthritis Research & Therapy 2006 8:R5 doi:10.1186/ar1847 |
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