Table 2

Genotype frequencies in UK Caucasian and North Indian/Pakistani rheumatoid arthritis patients and healthy controls

Gene

Genotype

UK Caucasian

North Indian/Pakistani


Control (n = 129)

RA (n = 147)

P

Nodular RA (n = 37)

P

Control (n = 128)

RA (n = 123)

P


FCGR2A-131

RR

39 (0.31)

40 (0.28)

0.81

7 (0.19)

0.36

25 (0.19)

30 (0.25)

0.15

RH

59 (0.47)

72 (0.49)

21 (0.58)

66 (0.52)

48 (0.39)

HH

28 (0.22)

34 (0.23)

8 (0.22)

37 (0.29)

44 (0.36)

FCGR3A-158

FF

68 (0.48)

59 (0.39)

0.15

12 (0.31)

0.02

63 (0.49)

48 (0.38)

0.21

FV

61 (0.43)

69 (0.46)

17 (0.45)

57 (0.44)

66 (0.52)

VV

12 (0.09)

22 (0.15)

9 (0.24)

9 (0.07)

12 (0.10)

FCGR3B-NA

22

48 (0.37)

55 (0.38)

0.13

16 (0.43)

0.28

49 (0.39)

47 (0.39)

0.25

21

72 (0.56)

71 (0.48)

16 (0.43)

45 (0.35)

53 (0.43)

11

9 (0.07)

21 (0.14)

5 (0.14)

33 (0.26)

22 (0.18)

FCGR2B-1206

GG

56 (0.48)

67 (0.46)

0.96

16 (0.43)

0.19

61 (0.48)

58 (0.47)

0.98

GA

50 (0.42)

63 (0.43)

13 (0.35)

54 (0.43)

54 (0.44)

AA

12 (0.10)

16 (0.11)

8 (0.22)

11 (0.09)

11 (0.09)


Values are expressed as number (%). RA, rheumatoid arthritis.

Morgan et al. Arthritis Research & Therapy 2006 8:R5   doi:10.1186/ar1847

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