Figure 5.

Effect of IB-MECA treatment on the expression level of key signaling proteins downstream to A₃ adenosine receptor (A₃AR) activation in synovia cells. The level of PI3K, pPKB/Akt, IKKα/β, NF-κB, TNF-α and caspase-3 was examined by western blot analysis. AIA, adjuvant-induced arthritis.