Arthritis Research & Therapy

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The PI3K–NF-κB signal transduction pathway is involved in mediating the anti-inflammatory effect of IB-MECA in adjuvant-induced arthritis

Pnina Fishman*, Sara Bar-Yehuda, Lea Madi, Lea Rath-Wolfson, Avivit Ochaion, Shira Cohen and Ehud Baharav

Arthritis Research & Therapy 2006, 8:R33 doi:10.1186/ar1887

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Methotrexate enhances the anti-inflammatory effect of CF101 via up-regulation of the A3 adenosine receptor expression

Avivit Ochaion, Sara Bar-Yehuda, Shira Cohn, Luis Del Valle, Georginia Perez-Liz, Lea Madi, Faina Barer, Motti Farbstein, Sari Fishman-Furman, Tatiana Reitblat, Alexander Reitblat, Howard Amital, Yair Levi, Yair Molad, Reuven Mader, Moshe Tishler, Pnina Langevitz, Alexander Zabutti, Pnina Fishman Arthritis Research & Therapy 2006, 8:R169 (13 November 2006)

Abstract | Full text | PDF | PubMed | Editor’s summary

Methotrexate potentiates the effects of the new anti-inflammatory CF101 in vivo, which supports the combined use of these drugs to treat rheumatoid arthritis.

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