Table 1

mRNA levels of the genes studied upon tumor necrosis factor-α activation

Gene product

Fold increase

CD31

0.8 ± 0.1

E-selectin

3,778 ± 200

Vascular cell adhesion molecule-1

637 ± 12

Intercellular adhesion molecule -1

245 ± 7.0

IL-6

5.3 ± 0.2

IL-8

9.9 ± 0.5

Tie-2

3.6 ± 0.1

Vascular endothelial growth factor-A

3.1 ± 0.1

Data are expressed as basal gene expression levels in non-stimulated human umbilical vein endothelial cells set at 1. Results are expressed as the mean ± standard deviation (n = 3).

Ogawara et al. Arthritis Research & Therapy 2006 8:R32   doi:10.1186/ar1885