Table 2

One year drug survival of first and second tumor necrosis factor antagonist, by diagnosis

Diagnosis

Rank of treatment

Number starting

Number failed

Survival (95% CI)

Rheumatoid arthritis

First

2,235

518

0.83 (0.82–0.84)

Second

194

72

0.79 (0.74–0.83)

Ankylosing spondylitis

First

300

49

0.89 (0.86–0.92)

Second

8

1

0.95 (0.72–0.99)

Psoriatic arthritis

First

289

55

0.87 (0.83–0.90)

Second

15

8

0.81 (0.65–0.90)

Juvenile idiopathic arthritis

First

126

16

0.90 (0.84–0.94)

Second

7

7

0.49 (0.22–0.72)

All differences between survival curves in first and second treatment for each diagnosis have a p > 0.001.

Gomez-Reino et al. Arthritis Research & Therapy 2006 8:R29   doi:10.1186/ar1881